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Other strengths and forms by Ziska Pharmaceuticals Ltd.
Indications & Uses
Laxibat is indicated for:
Pharmacology
Elobixibat blocks the ileal bile acid transporter (IBAT), which sits on the epithelial cells of the terminal ileum and normally takes bile acid back into the body. With reabsorption inhibited, more bile acid passes into the large intestine. There, the bile acid draws water and electrolytes into the lumen and also makes the colon move more. This is how Elobixibat relieves constipation.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults usually take Elobixibat 10 mg orally once a day, before a meal. The doctor may adjust the dose depending on the patient's symptoms, but the daily dose must not go above 15 mg.
Elderly patients generally have reduced physiological functions, so caution is needed, for example by reducing the dose.
In children, safety has not been established. This covers low-birth-weight infants, neonates, nursing infants, infants and pediatric patients, as there is no clinical experience in these groups.
Side Effects
Elobixibat is generally well tolerated by people with chronic constipation. In clinical studies, the side effects reported were abdominal pain, diarrhea, nausea, abdominal discomfort, soft faeces, abdominal distension and abnormal liver function test results. If liver function test abnormalities are found, the patient's symptoms should be watched carefully, and if necessary, Elobixibat should be stopped.
Cautions & Contraindications
Warnings & Precautions
Precaution concerning indication: there is no clinical experience of using Elobixibat in constipation caused by other drugs or by another disease. Precaution concerning dosage and administration: Elobixibat may cause abdominal pain or diarrhea. Depending on the patient's symptoms, the doctor should consider reducing the dose, withdrawing the drug or stopping it altogether. The need to continue Elobixibat should be checked carefully at regular intervals, so that treatment doesn't carry on without a clear purpose. Careful administration: in patients with serious liver disorder, Elobixibat may not work as well as expected, because of biliary obstruction, reduced bile acid secretion and similar causes.
Contraindications
Elobixibat must not be given to anyone who is hypersensitive to the active substance or to any of the excipients. It also must not be used in patients with a documented intestinal obstruction linked to a tumor or hernia, or where such a condition is suspected, because the obstruction may get worse.
Pregnancy & Breastfeeding
During Pregnancy: Pregnant women, and women who may be pregnant, should use Elobixibat only if the expected benefit of the treatment outweighs the possible risks.
During Lactation: Women who are breastfeeding should avoid Elobixibat. If treatment with Elobixibat is essential, breast feeding must be stopped for the duration of treatment.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
No data is available on overdose with Elobixibat, so don't go above the dose that is indicated. If a person does take too much, watch them closely so that any problem can be dealt with in time.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Elobixibat below 25°C and protect it from light. Keep it out of reach of children.
Drug Interactions
Common questions about Laxibat 5 mg
What is Laxibat 5 mg Tablet?
Laxibat 5 mg Tablet is a medicine that contains Elobixibat. It is made by Ziska Pharmaceuticals Ltd. It belongs to the Osmotic purgatives group of medicines.
What is Laxibat used for?
Laxibat is used for: Constipation.
What are the side effects of Laxibat?
Elobixibat is generally well tolerated by people with chronic constipation. In clinical studies, the side effects reported were abdominal pain, diarrhea, nausea, abdominal discomfort, soft faeces, abdominal distension and abnormal liver function test results.
Can I take Laxibat during pregnancy or while breastfeeding?
During Pregnancy: Pregnant women, and women who may be pregnant, should use Elobixibat only if the expected benefit of the treatment outweighs the possible risks. During Lactation: Women who are breastfeeding should avoid Elobixibat. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Laxibat?
No data is available on overdose with Elobixibat, so don't go above the dose that is indicated. If a person does take too much, watch them closely so that any problem can be dealt with in time. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Laxibat?
Store Elobixibat below 25°C and protect it from light. Keep it out of reach of children.
Can I take other medicines with Laxibat?
Some medicines can interact with Elobixibat, for example: Ursodeoxycholic Acid, Midazolam, Sucralfate, Digoxin, Cholestyramine, Dabigatran Etexilate. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Laxibat is already among the lowest-priced brands of Elobixibat at this strength.
Do I need a prescription for Laxibat?
Laxibat is a prescription (Rx) medicine. Take it as your doctor advises.