Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Larcadip is indicated for:
Pharmacology
Lercanidipine is a dihydropyridine-type calcium channel blocker that acts selectively, reducing the flow of calcium into the smooth muscle cells lining blood vessels. It lowers blood pressure mainly by relaxing this vascular smooth muscle directly, which brings down overall resistance in the peripheral blood vessels. Because it partitions strongly into cell membranes, its blood-pressure-lowering effect lasts for an extended period, and its high selectivity for blood vessels means it does not weaken the force of the heart's contractions.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Use in the elderly: The usual starting dose is 10 mg by mouth once daily, taken at least 15 minutes before a meal. Depending on how the individual patient responds, this may be increased to 20 mg. It can take around 2 weeks for the full blood-pressure-lowering effect to become apparent. Patients whose blood pressure is not adequately controlled on a single antihypertensive may benefit from adding Lercanidipine to treatment with a beta-blocker (atenolol), a diuretic (hydrochlorothiazide), or an ACE inhibitor (ramipril).
Use in children: There is no clinical data for patients under 18 years of age, so use in children is not currently recommended.
Use in renal or hepatic impairment: Caution is needed in patients with mild to moderate kidney or liver impairment, and doses above 20 mg daily should be approached carefully. Lercanidipine is not recommended for patients with severe hepatic or renal impairment.
Side Effects
Treatment with Lotensyl is generally well tolerated. The most commonly reported side effects stem from Lotensyl's vasodilatory action and include flushing, swelling of the lower limbs, headache, dizziness and weakness. Other effects, seen in fewer than 1% of patients, include tiredness; digestive complaints such as indigestion, nausea, vomiting, upper abdominal pain and diarrhea; along with excessive urination, skin rash, drowsiness and muscle pain.
Cautions & Contraindications
Warnings & Precautions
Special care is needed when giving Lotensyl to patients with sick sinus syndrome, left ventricular dysfunction, or ischaemic heart disease.
Contraindications
Lercanidipine should not be used in patients with left ventricular outflow tract obstruction, untreated congestive cardiac failure, unstable angina pectoris, a myocardial infarction within the past 1 month, or known hypersensitivity to any dihydropyridine. It should also not be taken with grapefruit juice.
Pregnancy & Breastfeeding
There is no clinical data on lercanidipine in pregnancy, so it should not be given during pregnancy, or to women who could become pregnant, unless effective contraception is being used. Lercanidipine is highly lipophilic, and it may be expected to pass into breast milk. For that reason it should not be given to a mother who is breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
There is no data on overdosage with Lercanidipine Hydrochloride. With other dihydropyridines, though, an overdose would be expected to cause excessive peripheral vasodilation, with marked hypotension and reflex tachycardia. Lercanidipine Hydrochloride is highly lipophilic, so plasma levels most probably don't show how long the period of risk will last, and dialysis may not be effective.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Lercanidipine Hydrochloride below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Drug Interactions
Common questions about Larcadip 10 mg
What is Larcadip 10 mg Tablet?
Larcadip 10 mg Tablet is a medicine that contains Lercanidipine Hydrochloride. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Calcium-channel blockers group of medicines.
What is Larcadip used for?
Larcadip is used for: Hypertension.
What are the side effects of Larcadip?
Treatment with Lotensyl is generally well tolerated. The most commonly reported side effects stem from Lotensyl's vasodilatory action and include flushing, swelling of the lower limbs, headache, dizziness and weakness.
Can I take Larcadip during pregnancy or while breastfeeding?
There is no clinical data on lercanidipine in pregnancy, so it should not be given during pregnancy, or to women who could become pregnant, unless effective contraception is being used. Lercanidipine is highly lipophilic, and it may be expected to pass into breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Larcadip?
There is no data on overdosage with Lercanidipine Hydrochloride. With other dihydropyridines, though, an overdose would be expected to cause excessive peripheral vasodilation, with marked hypotension and reflex tachycardia. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Larcadip?
Store Lercanidipine Hydrochloride below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Can I take other medicines with Larcadip?
Some medicines can interact with Lercanidipine Hydrochloride, for example: Erythromycin, Carbamazepine, Rifampicin, Midazolam, Itraconazole, Ritonavir. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Larcadip is already among the lowest-priced brands of Lercanidipine Hydrochloride at this strength.
Do I need a prescription for Larcadip?
Larcadip is a prescription (Rx) medicine. Take it as your doctor advises.