Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Larcadip is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Use in the elderly: The usual starting dose is 10 mg by mouth once daily, taken at least 15 minutes before a meal. Depending on how the individual patient responds, this may be increased to 20 mg. It can take around 2 weeks for the full blood-pressure-lowering effect to become apparent. Patients whose blood pressure is not adequately controlled on a single antihypertensive may benefit from adding Lercanidipine to treatment with a beta-blocker (atenolol), a diuretic (hydrochlorothiazide), or an ACE inhibitor (ramipril). Use in children: There is no clinical data for patients under 18 years of age, so use in children is not currently recommended. Use in renal or hepatic impairment: Caution is needed in patients with mild to moderate kidney or liver impairment, and doses above 20 mg daily should be approached carefully. Lercanidipine is not recommended for patients with severe hepatic or renal impairment.
Side Effects
Treatment with Lotensyl is generally well tolerated. The most commonly reported side effects stem from Lotensyl's vasodilatory action and include flushing, swelling of the lower limbs, headache, dizziness and weakness. Other effects, seen in fewer than 1% of patients, include tiredness; digestive complaints such as indigestion, nausea, vomiting, upper abdominal pain and diarrhea; along with excessive urination, skin rash, drowsiness and muscle pain.
Cautions & Contraindications
Warnings & Precautions
Special care is needed when giving Lotensyl to patients with sick sinus syndrome, left ventricular dysfunction, or ischaemic heart disease.
Contraindications
Lercanidipine should not be used in patients with left ventricular outflow tract obstruction, untreated congestive cardiac failure, unstable angina pectoris, a myocardial infarction within the past 1 month, or known hypersensitivity to any dihydropyridine. It should also not be taken with grapefruit juice.