Pricing
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Lantus SoloStar is indicated for:
Pharmacology
Insulin Glargine is a sterile solution that you inject under the skin (subcutaneous injection). It is a recombinant human insulin analogue, made by recombinant DNA technology, and it works as a long-acting blood glucose lowering medicine for injection, with a duration of action of up to 24 hours.
Its main job is to regulate glucose metabolism. Insulin glargine, like other insulins and their analogues, lowers blood glucose in two ways. It stimulates peripheral glucose uptake, mainly by skeletal muscle and fat, and it inhibits glucose production in the liver. Insulin also inhibits lipolysis and proteolysis, and it enhances protein synthesis.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Insulin Glargine has a fairly steady glucose-lowering effect over 24 hours, so it can be given once a day. Its potency is about the same as human insulin. It is recommended as a once-daily subcutaneous injection and can be given at any time of the day, but once you start, give it at the same time every day. The dose must be individualized based on clinical response. Blood glucose monitoring is essential in all patients with diabetes. In patients with type 1 diabetes, it must be used in regimens with short-acting insulin. It is not recommended for intravenous use, because giving the usual subcutaneous dose intravenously could result in severe hypoglycemia. Initiation of Insulin Glargine therapy: in patients with type 1 diabetes, the recommended starting dose is approximately one-third of the total daily insulin requirements. Short-acting, premeal insulin should then cover the rest of the daily insulin requirements. In patients with type 2 diabetes who are not currently treated with insulin, the recommended starting dose is 10 units (or 0.2 Units/kg) once daily, and this should then be adjusted to the patient's needs. Converting to Insulin Glargine from other insulin therapies: if a patient changes from a regimen with an intermediate- or long-acting insulin, the amount and timing of shorter-acting insulins may need to be adjusted, and so may the doses of any oral anti-diabetic drugs. When moving a patient from once-daily NPH insulin, the recommended initial dose of Insulin Glargine is the same as the dose of NPH being discontinued. When moving a patient from twice-daily NPH insulin to once-daily Insulin Glargine, the recommended initial dose is 80% of the total NPH dose being discontinued.
Side Effects
Insulin Glargine can cause hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, pruritus and rash.
Cautions & Contraindications
Warnings & Precautions
Dose adjustment and monitoring Check blood glucose in every patient treated with insulin. Change Insulin Glargine regimens carefully, and only under medical supervision. Administration Don't dilute Insulin Glargine or mix it with any other insulin or solution. Don't give it subcutaneously through an insulin pump, and don't give it intravenously, because severe hypoglycemia can occur. Renal or hepatic impairment In these cases the Semgleedose may need to be reduced.
Contraindications
Don't give insulin glargine to anyone who is allergic to it, or to any of the other ingredients in the product (the excipients).
Pregnancy & Breastfeeding
Insulin glargine is in pregnancy category C. That means it should be used during pregnancy only if the possible benefit to the mother justifies the possible risk to the fetus.
It is not known whether insulin glargine passes into human milk. Many drugs do, including human insulin, so a doctor should be careful when giving insulin glargine to a nursing woman. Women who are breastfeeding may need their insulin dose and their diet adjusted.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Taking too much Insulin Glargine can cause hypoglycemia, which is low blood sugar. A mild episode can usually be treated with carbohydrates taken by mouth. Severe hypoglycemia may need glucose given parenterally or an injection of glucagon. The dose of the medicine, the pattern of meals or the amount of exercise may also need to be adjusted.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Insulin Glargine in a refrigerator at 2°C to 8°C. Don't let it freeze, and keep it away from light.
Drug Interactions
Common questions about Lantus SoloStar 100 IU/ml
What is Lantus SoloStar 100 IU/ml SC Injection?
Lantus SoloStar 100 IU/ml SC Injection is a medicine that contains Insulin Glargine. It is made by Synovia Pharma PLC. It belongs to the Long Acting Insulin group of medicines.
What is Lantus SoloStar used for?
Lantus SoloStar is used for: Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus, Diabetes Mellitus.
What are the side effects of Lantus SoloStar?
Insulin Glargine can cause hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, pruritus and rash.
Can I take Lantus SoloStar during pregnancy or while breastfeeding?
Insulin glargine is in pregnancy category C. That means it should be used during pregnancy only if the possible benefit to the mother justifies the possible risk to the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Lantus SoloStar?
Taking too much Insulin Glargine can cause hypoglycemia, which is low blood sugar. A mild episode can usually be treated with carbohydrates taken by mouth. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Lantus SoloStar?
Keep Insulin Glargine in a refrigerator at 2°C to 8°C. Don't let it freeze, and keep it away from light.
Can I take other medicines with Lantus SoloStar?
Some medicines can interact with Insulin Glargine, for example: Disopyramide, Pentoxifylline, Danazol, Fluoxetine, Clonidine Hydrochloride, Insulin (Human) 30/70. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Lantus SoloStar?
Lantus SoloStar is a prescription (Rx) medicine. Take it as your doctor advises.