Pricing
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All price changes →Indications & Uses
Human Anti-D Immunoglobulins are used in Rh-negative women for pregnancy and other obstetrical conditions, unless the father or the baby is conclusively Rh negative. These conditions are: Pregnancy or delivery of an Rh-positive baby, whatever the ABO groups of the mother and baby are Abortion or threatened abortion at any stage of gestation Ectopic pregnancy Antepartum fetal-maternal hemorrhage (suspected or proven) that results from antepartum hemorrhage (for example, placenta previa), amniocentesis, chorionic villus sampling, percutaneous umbilical blood sampling, another obstetrical manipulative procedure (for example, version) or abdominal trauma Transfusion of Rh incompatible blood or blood products Human Anti-D Immunoglobulins are also used in transfusion, to prevent Rh immunization in any Rh-negative person after an incompatible transfusion of Rh-positive blood or blood products (for example, red blood cells, platelet concentrates, granulocyte concentrates).
Pharmacology
Anti-D immunoglobulin stops a rhesus-negative mother from making her own antibodies against rhesus-positive red blood cells (RBCs) from the baby. These cells can get into the mother's blood during childbirth, abortion or certain other sensitising events. The medicine is also used in idiopathic thrombocytopenic purpura, where it helps prevent excessive bleeding.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Give one dose of 250 mcg by IM injection as soon as possible after delivery of an Rh-positive child, or after abortion. It is best given within 48 hours, but not later than 72 hours post-partum.
Following any potentially sensitizing episode (e.g. stillbirth, amniocentesis) up to 20 weeks of gestation, the dose is 125 mcg per episode, given immediately or within 72 hours. After 20 weeks of gestation, the dose is 250 mcg.
For antenatal prophylaxis, give 250 mcg in week 28 and again in week 34 of pregnancy. The injection must only be given deep intramuscularly. Do not inject it intravenously.
Side Effects
Human Anti-D Immunoglobulins can cause hypersensitivity reactions such as hives, wheezing and urticaria. There may be pain and tenderness at the injection site. Fever, chills, nausea, facial flushing and headache can also occur.
Cautions & Contraindications
Warnings & Precautions
When Human Anti-D Immunoglobulins is used after childbirth, it should be given to the mother only. It is not for people who are rhesus-positive. After the injection, keep the patient under observation for 20 minutes.
Pregnancy & Breastfeeding
Human Anti-D Immunoglobulins fall under Pregnancy Category C. This means either animal studies have shown harmful effects on the foetus (teratogenic, embryocidal or other), and there are no controlled studies in women, or no studies are available in women or in animals. The medicine should be given only if the possible benefit justifies the possible risk to the foetus.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Human Anti-D Immunoglobulins in a cool, dry place.
Common questions about IMMUNORho 300 mcg/2 ml
What is IMMUNORho 300 mcg/2 ml IM Injection?
IMMUNORho 300 mcg/2 ml IM Injection is a medicine that contains Human Anti-D Immunoglobulins. It is made by ZAS Corporation. It belongs to the Vaccines group of medicines.
What is IMMUNORho used for?
Human Anti-D Immunoglobulins are used in Rh-negative women for pregnancy and other obstetrical conditions, unless the father or the baby is conclusively Rh negative. These conditions are: Pregnancy or delivery of an Rh-positive baby, whatever the ABO groups of the mother and baby are Abortion or threatened abortion at any stage of gestation Ectopic pregnancy Antepartum fetal-maternal hemorrhage (suspected or proven) that results from antepartum hemorrhage (for example, placenta previa), amniocentesis, chorionic villus sampling, percutaneous umbilical blood sampling, another obstetrical manipulative procedure (for example, version) or abdominal trauma Transfusion of Rh incompatible blood or blood products Human Anti-D Immunoglobulins are also used in transfusion, to prevent Rh immunization in any Rh-negative person after an incompatible transfusion of Rh-positive blood or blood products (for example, red blood cells, platelet concentrates, granulocyte concentrates).
What are the side effects of IMMUNORho?
Human Anti-D Immunoglobulins can cause hypersensitivity reactions such as hives, wheezing and urticaria. There may be pain and tenderness at the injection site.
Can I take IMMUNORho during pregnancy or while breastfeeding?
Human Anti-D Immunoglobulins fall under Pregnancy Category C. This means either animal studies have shown harmful effects on the foetus (teratogenic, embryocidal or other), and there are no controlled studies in women, or no studies are available in women or in animals. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store IMMUNORho?
Keep Human Anti-D Immunoglobulins in a cool, dry place.
Do I need a prescription for IMMUNORho?
IMMUNORho is a prescription (Rx) medicine. Take it as your doctor advises.