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Other brands with the same active ingredient
These brands contain the same active ingredient (Iloperidone). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Ilodon 6 is indicated for:
Pharmacology
Iloperidone binds strongly to dopamine D2 receptors in the caudate nucleus and putamen of the brains of people with schizophrenia, and it occupies these receptors to the maximum extent. The improvement in cognition is put down to iloperidone's strong affinity for α adrenergic receptors. It also binds strongly to serotonin 5-HT2a and dopamine D3 receptors. Its binding to dopamine D4, serotonin 5-HT6 and 5-HT7, and norepinephrine NEα1 receptors is moderate. Iloperidone binds only weakly to serotonin 5-HT1A, dopamine D1, and histamine H1 receptors.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Iloperidone must be titrated slowly to avoid orthostatic hypotension. Because of this need to titrate slowly, control of symptoms may be delayed during the first 1 to 2 weeks of treatment. Administer Iloperidone orally twice daily, without regard to meals, and titrate the dosage to avoid orthostatic hypotension. For schizophrenia, the starting dosage is 1 mg twice daily and the recommended dosage is 6 mg to 12 mg twice daily. For bipolar mania, the starting dosage is 1 mg twice daily and the recommended dosage is 12 mg twice daily. In children and adolescents, safety and effectiveness have not been established. Iloperidone is not recommended for patients with severe hepatic impairment.
Side Effects
The side effects seen most often (occurring in at least 5% of patients and at least 2 times more frequently than with placebo) were as follows. In schizophrenia: dizziness, dry mouth, tiredness, blocked nose, a drop in blood pressure on standing (orthostatic hypotension), drowsiness, fast heartbeat, and weight gain. In bipolar mania: fast heartbeat, dizziness, dry mouth, raised liver enzymes, blocked nose, weight gain, low blood pressure, and drowsiness.
Cautions & Contraindications
Warnings & Precautions
Cerebrovascular adverse reactions in elderly patients with dementia-related psychosis: there is an increased incidence of cerebrovascular adverse reactions, such as stroke and transient ischaemic attack. QT prolongation: Iloperidone prolongs the QT interval and may be associated with arrhythmia and sudden death. Avoid using FANAPT together with other drugs known to prolong QTc. Use caution, and consider adjusting the dose, when prescribing FANAPT with other drugs that inhibit FANAPT metabolism. Monitor serum potassium and magnesium in patients at risk of electrolyte disturbances. Neuroleptic malignant syndrome (NMS): manage by stopping the drug immediately and monitoring the patient closely. Tardive dyskinesia: discontinue treatment if clinically appropriate. Metabolic changes: monitor for hyperglycaemia or diabetes mellitus, dyslipidaemia, and weight gain. Orthostatic hypotension and syncope: monitor heart rate and blood pressure, and warn patients who have known cardiovascular or cerebrovascular disease, or who are at risk of dehydration or syncope. Seizures: use with caution in patients with a history of seizures or with conditions that lower the seizure threshold. Leukopenia, neutropenia, and agranulocytosis have been reported with antipsychotics. Perform complete blood counts (CBC) in patients with a pre-existing low white blood cell count (WBC) or a history of leukopenia or neutropenia. Consider stopping FANAPT if a clinically significant fall in WBC occurs without any other identifiable cause. Priapism: cases have been reported in association with FANAPT treatment. Severe priapism may require surgical intervention. Potential for cognitive and motor impairment: use caution when operating machinery. Intraoperative floppy iris syndrome (IFIS): IFIS during cataract surgery may require changes to the surgical technique.
Contraindications
Known hypersensitivity to Iloperidone or to any ingredient in the formulation.
Pregnancy & Breastfeeding
Pregnancy: Exposure during the third trimester may cause extrapyramidal and/or withdrawal symptoms in the newborn.
Lactation: It is not known whether iloperidone or its metabolites pass into human breast milk, nor is it known what effect this may have on a breastfed child or on milk production. Iloperidone has been found to pass into the milk of rats.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Iloperidone tablets at a controlled room temperature of 25°C. Short periods between 15° and 30°C are allowed.
Common questions about Ilodon 6 6 mg
What is Ilodon 6 6 mg Tablet?
Ilodon 6 6 mg Tablet is a medicine that contains Iloperidone. It is made by Beacon Pharmaceuticals PLC. It belongs to the Piperidinyl-benzisoxazole derivative group of medicines.
What is Ilodon 6 used for?
Ilodon 6 is used for: Schizophrenia.
What are the side effects of Ilodon 6?
The side effects seen most often (occurring in at least 5% of patients and at least 2 times more frequently than with placebo) were as follows. In schizophrenia: dizziness, dry mouth, tiredness, blocked nose, a drop in blood pressure on standing (orthostatic hypotension), drowsiness, fast heartbeat, and weight gain.
Can I take Ilodon 6 during pregnancy or while breastfeeding?
Pregnancy: Exposure during the third trimester may cause extrapyramidal and/or withdrawal symptoms in the newborn. Lactation: It is not known whether iloperidone or its metabolites pass into human breast milk, nor is it known what effect this may have on a breastfed child or on milk production. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Ilodon 6?
Keep Iloperidone tablets at a controlled room temperature of 25°C. Short periods between 15° and 30°C are allowed.
Do I need a prescription for Ilodon 6?
Ilodon 6 is a prescription (Rx) medicine. Take it as your doctor advises.