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Other strengths and forms by Square Pharmaceuticals PLC, Pabna
Indications & Uses
Fosfomax is indicated for:
Pharmacology
Fosfomycin kills bacteria that are actively multiplying, and it does this by stopping the enzymes that build the bacterial cell wall. It works at the very first stage of cell wall formation inside the bacterial cell, where it blocks the making of peptidoglycan.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Detailed dosing reference is not available yet. Please follow your prescription and consult your pharmacist.
Side Effects
During treatment with Fosfomycin Sodium, the side effects people report most often are stomach and bowel upsets and reactions at the injection site. Low potassium in the blood (hypokalaemia) and/or high sodium in the blood (hypernatraemia) are other important side effects.
Cautions & Contraindications
Warnings & Precautions
Fosfomycin Sodium is preferably given together with other antibiotics, because this helps avoid cross resistance developing. The medicine carries a high sodium load, and that can lower potassium levels in serum or plasma. So a low-sodium diet is recommended during treatment, and in some cases potassium may need to be given as a substitute. Serum electrolyte levels and water balance must be monitored throughout therapy. Take care when using fosfomycin in patients with cardiac insufficiency, hypertension, hyperaldosteronism, hypernatraemia or pulmonary edema. Acute, potentially life-threatening hypersensitivity reactions (anaphylactic shock) may occur in very rare cases. At the first signs, which include sweating, nausea and cyanosis, the fosfomycin infusion must be stopped immediately.
Contraindications
Don't use Fosfomycin Sodium if you are allergic to fosfomycin or to any of the other ingredients in the medicine.
Use in Special Populations
Dosage in renal insufficiency: Take special care if you are considering doses at the higher end of the recommended range. In patients with impaired renal function, the dose of fosfomycin must be adjusted to the degree of renal impairment.
Hepatic impairment: There are no data showing that a dose adjustment is needed in patients with hepatic impairment.
Elderly patients: Use the recommended adult doses in elderly patients. Be careful when considering doses at the higher end of the recommended range.
Pediatric population: Dose recommendations are based on very limited data.
Neonates, infants and children <12 years of age (<40 kg): The dose of fosfomycin in children should be based on age and body weight (BW).
Premature neonates (age <40 weeks): 100 mg/kg BW in 2 divided doses
Neonates (age 40 to 44 weeks): 200 mg/kg BW in 3 divided doses
Infants 1 to 12 months (up to 10 kg BW): 200 to 300 b mg/kg BW in 3 divided doses
Infants and children aged 1 to 12 years (10 to 40 kg BW): 200 to 400 b mg/kg BW in 3 to 4 divided doses
Overdose
There isn't much experience with fosfomycin overdose. With parenteral use of fosfomycin, cases of hypotonia, somnolence, electrolyte disturbances, thrombocytopenia and hypoprothrombinemia have been reported.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Fosfomycin Sodium below 30° C, away from light and moisture, and keep it out of the reach of children. Once it has been mixed with the solvent, use it straight away. If that isn't possible, it can be kept in a refrigerator (at 2-8°C), protected from light, for up to 24 hours.
Common questions about Fosfomax 4 gm
What is Fosfomax 4 gm IV Infusion?
Fosfomax 4 gm IV Infusion is a medicine that contains Fosfomycin Sodium. It is made by Square Pharmaceuticals PLC, Pabna. It belongs to the Intracellular antibiotic group of medicines.
What is Fosfomax used for?
Fosfomax is used for: Respiratory Tract Infection.
What are the side effects of Fosfomax?
During treatment with Fosfomycin Sodium, the side effects people report most often are stomach and bowel upsets and reactions at the injection site. Low potassium in the blood (hypokalaemia) and/or high sodium in the blood (hypernatraemia) are other important side effects.
What happens if I take too much Fosfomax?
There isn't much experience with fosfomycin overdose. With parenteral use of fosfomycin, cases of hypotonia, somnolence, electrolyte disturbances, thrombocytopenia and hypoprothrombinemia have been reported. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Fosfomax?
Store Fosfomycin Sodium below 30° C, away from light and moisture, and keep it out of the reach of children. Once it has been mixed with the solvent, use it straight away.
Do I need a prescription for Fosfomax?
Fosfomax is a prescription (Rx) medicine. Take it as your doctor advises.