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Same active ingredient — pay up to 20% less
These brands contain the same active ingredient (Ezetimibe). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Ezetim is indicated for:
Pharmacology
Ezetimibe works at the brush border of the small intestine, where it blocks cholesterol absorption by acting on the sterol transporter Niemann-Pick C1-Like1 (NPC1L1). Less cholesterol then reaches the liver, hepatic cholesterol stores fall, and clearance of cholesterol from the blood increases.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The patient should follow a suitable lipid lowering diet and continue this diet throughout treatment with Ezetimibe.
Adult Dose: The recommended dose is one Ezetimibe 10 mg tablet once daily. Ezetimibe can be taken at any time of day, with or without food.
Use in the elderly: No dosage adjustment is required for elderly patients.
Pediatric Use: For pediatric patients aged 10 to 17 years, no dosage adjustment is required, though clinical experience in pediatric and adolescent patients remains limited. When Ezetimibe is given together with a statin, the dosing instructions for that statin in adolescents should be consulted. For pediatric patients below age 10, Ezetimibe is not recommended, since safety and efficacy data in this age group are insufficient.
Use in hepatic impairment: No dosage adjustment is required for patients with mild hepatic insufficiency (Child Pugh score 5 to 6). Treatment with Ezetimibe is not recommended for patients with moderate (Child Pugh score 7 to 9) or severe (Child Pugh score above 9) liver dysfunction.
Use in renal impairment: No dosage adjustment is required for patients with renal impairment.
Side Effects
Ezetrol (used alone or together with an HMG-CoA reductase inhibitor) was generally well tolerated in clinical studies. The overall rate of adverse events reported with Ezetrol was similar to that seen with placebo, and a similar proportion of patients on Ezetrol and on placebo stopped treatment because of adverse events. Adverse reactions seen in patients treated with Ezetrol included the following. Common or very common: fatigue, gastro-intestinal disturbances, headache, muscle pain. Rare: anaphylaxis, angioedema, joint pain, hepatitis, hypersensitivity reactions, rash. Very rare: cholecystitis, gallstones, myopathy, pancreatitis, raised creatine kinase, rhabdomyolysis, and a drop in platelet count (thrombocytopenia).
Cautions & Contraindications
Warnings & Precautions
Concurrent use of Ezetrol with a specific HMG-CoA reductase inhibitor (statin) should follow the prescribing information provided for that particular statin.
Contraindications
Ezetimibe should not be used by anyone who is allergic to any of its ingredients. Taking it together with an HMG-CoA reductase inhibitor is also not allowed for people who have active liver disease or whose blood transaminase levels stay raised without a clear reason.
Pregnancy & Breastfeeding
Pregnancy: Ezetimibe should only be used in pregnancy if it is clearly needed, as no clinical data exist on its use in pregnant women. Animal studies of ezetimibe used alone have not shown any direct or indirect harm to pregnancy, embryo-foetal development, birth, or development after birth.
Breastfeeding: Ezetimibe should not be used while breastfeeding. Studies in rats have shown that ezetimibe passes into breast milk; whether it passes into human breast milk is not known.
Fertility: No clinical data are available. Non-clinical studies have not shown any effect on fertility.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
In clinical studies, Ezetimibe was given at 50 mg/day to 15 healthy subjects for up to 14 days, and at 40 mg/day to 18 patients with primary hypercholesterolaemia for up to 56 days. It was generally well tolerated in both groups. In animals, no toxicity was seen after single oral doses of 5000 mg/kg in rats and mice, or 3000 mg/kg in dogs.
A few cases of Ezetimibe overdosage have been reported. Most were not linked to any adverse experiences, and the ones that were reported were not serious. If an overdose happens, symptomatic and supportive measures should be used.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Ezetimibe should be dispensed only by, or on the prescription of, a registered physician. Keep it out of the reach of children. Store it below 30°C in a cool, dry place, and protect it from light and moisture.
Drug Interactions
Common questions about Ezetim 10 mg
What is Ezetim 10 mg Tablet?
Ezetim 10 mg Tablet is a medicine that contains Ezetimibe. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Ezetimibe group of medicines.
What is Ezetim used for?
Ezetim is used for: Hyperlipidemia.
What are the side effects of Ezetim?
Ezetrol (used alone or together with an HMG-CoA reductase inhibitor) was generally well tolerated in clinical studies. The overall rate of adverse events reported with Ezetrol was similar to that seen with placebo, and a similar proportion of patients on Ezetrol and on placebo stopped treatment because of adverse events.
Can I take Ezetim during pregnancy or while breastfeeding?
Pregnancy: Ezetimibe should only be used in pregnancy if it is clearly needed, as no clinical data exist on its use in pregnant women. Animal studies of ezetimibe used alone have not shown any direct or indirect harm to pregnancy, embryo-foetal development, birth, or development after birth. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Ezetim?
In clinical studies, Ezetimibe was given at 50 mg/day to 15 healthy subjects for up to 14 days, and at 40 mg/day to 18 patients with primary hypercholesterolaemia for up to 56 days. It was generally well tolerated in both groups. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Ezetim?
Ezetimibe should be dispensed only by, or on the prescription of, a registered physician. Keep it out of the reach of children.
Can I take other medicines with Ezetim?
Some medicines can interact with Ezetimibe, for example: Rosuvastatin + Ezetimibe, Bempedoic Acid + Ezetimibe. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Ezeta by Beximco Pharmaceuticals Ltd. has the same ingredient and strength for ৳8.00 per unit, compared with ৳10.00 for Ezetim. Ask your doctor or pharmacist before switching.
Do I need a prescription for Ezetim?
Ezetim is a prescription (Rx) medicine. Take it as your doctor advises.