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These brands contain the same active ingredient (Eplerenone). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Erutic is indicated for:
Pharmacology
Eplerenone works by blocking aldosterone from attaching to its receptor in the body. It binds to the mineralocorticoid receptor, so aldosterone cannot act on it. Aldosterone is a hormone in the renin-angiotensin-aldosterone system (RAAS), and it is made mainly in the adrenal gland. Several things control how much is produced, including angiotensin II and other non-RAAS factors such as adrenocorticotropic hormone and potassium.
Aldosterone attaches to mineralocorticoid receptors in two kinds of tissue. One kind is epithelial tissue, such as the kidney. The other is nonepithelial tissue, such as the heart, blood vessels and brain. In these places it raises blood pressure by causing the body to hold on to sodium, and it may also work through other mechanisms.
Eplerenone causes plasma renin and serum aldosterone to stay raised over time. This happens because aldosterone normally acts as a brake on renin release, and eplerenone takes that brake off. The higher renin activity and aldosterone levels that follow do not cancel out the effect of eplerenone.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Congestive heart failure following a recent heart attack: The usual dose of Eplerenone for this condition is 50 mg once daily. Treatment is generally started at 25 mg once daily, with the dose increased to the 50 mg once-daily target within about 4 weeks, as the patient is able to tolerate it. Eplerenone can be taken with or without food.
Hypertension: Eplerenone may be used on its own or together with other blood pressure lowering medicines. The usual starting dose for hypertension is 50 mg once daily. If blood pressure is not adequately controlled on 50 mg once daily, the dose may be increased to 50 mg twice daily. Doses higher than this are not advised, since they do not lower blood pressure any further than 100 mg a day and carry a greater risk of high potassium levels in the blood.
Use in children: The safety and effectiveness of Eplerenone in pediatric patients have not been established.
Use in the elderly: No differences in overall effectiveness or safety were seen in geriatric patients compared with younger adults.
Side Effects
Headache, dizziness, diarrhoea, stomach pain, nausea, and cough or flu-like symptoms can occur while taking this medicine. Seek immediate medical attention if signs of a serious allergic reaction appear, such as rash, itching, swelling, severe dizziness, or trouble breathing.
Cautions & Contraindications
Warnings & Precautions
Aldonist should be used with caution in patients who have hyperkalemia, severe kidney disease, or diabetes with congestive heart failure after a recent heart attack, including those who also have proteinuria.
Contraindications
Eplerenone should not be used if you have hyperkalemia (high potassium in the blood). It is also not for people with severe kidney impairment, where creatinine clearance is less than 30 ml/min, or with severe liver impairment. Eplerenone must also not be taken together with strong CYPBA4 inhibitors. These include ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir and nelfinavir. Using it alongside other potassium-sparing diuretics is contraindicated too.
Pregnancy & Breastfeeding
Pregnancy: There are no adequate, well-controlled studies of Eplerenone use in pregnant women, so it should be used during pregnancy only if the expected benefit to the mother outweighs the possible risk to the unborn child.
Breastfeeding: It is not known whether Eplerenone passes into human breast milk after it is taken by mouth. Since many medicines do pass into breast milk and the possible effects on a nursing infant are not known, a decision should be made to either stop breastfeeding or stop the medicine, weighing how important it is for the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Eplerenone below 30°C in a cool, dry place, and keep it away from light and moisture. Keep it out of children's reach.
Drug Interactions
Common questions about Erutic 25 mg
What is Erutic 25 mg Tablet?
Erutic 25 mg Tablet is a medicine that contains Eplerenone. It is made by Drug International Ltd., Gopalpur. It belongs to the Potassium-sparing diuretics group of medicines.
What is Erutic used for?
Erutic is used for: Hypertension, Heart Failure, Myocardial Infarction.
What are the side effects of Erutic?
Headache, dizziness, diarrhoea, stomach pain, nausea, and cough or flu-like symptoms can occur while taking this medicine. Seek immediate medical attention if signs of a serious allergic reaction appear, such as rash, itching, swelling, severe dizziness, or trouble breathing.
Can I take Erutic during pregnancy or while breastfeeding?
Pregnancy: There are no adequate, well-controlled studies of Eplerenone use in pregnant women, so it should be used during pregnancy only if the expected benefit to the mother outweighs the possible risk to the unborn child. Breastfeeding: It is not known whether Eplerenone passes into human breast milk after it is taken by mouth. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Erutic?
Store Eplerenone below 30°C in a cool, dry place, and keep it away from light and moisture. Keep it out of children's reach.
Can I take other medicines with Erutic?
Some medicines can interact with Eplerenone, for example: Erythromycin, Fluconazole, Baclofen, Alfuzosin, Trimethoprim, Tacrolimus. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Erutic?
Erutic is a prescription (Rx) medicine. Take it as your doctor advises.