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These brands contain the same active ingredient (Pyridoxine Hydrochloride + Doxylamine Succinate). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Emedox is indicated for:
Pharmacology
Doxylamine Succinate is an antihistamine that blocks the histamine (H1) receptor. It can cross the blood brain barrier and has a high affinity for H1 receptors in the brain, so it blocks them there. It also lowers the action of histamine at the H1 receptor by inhibiting both the vestibular system and the muscarinic receptor. Its effect on the vestibular system reduces the stimulation of the vomiting center. The muscarinic receptor inhibition may also play a part in its antihistamine antiemetic activity.
Pyridoxine Hydrochloride is a vitamin B6 analog. It is used to prevent nausea and vomiting because of its antiemetic properties.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Start with one tablet by mouth at bedtime on Day 1. If that dose controls your symptoms the next day, keep taking one tablet at bedtime each day. If symptoms are still there on Day 2, increase to one tablet in the morning and one tablet at bedtime. The maximum recommended dose is two tablets a day, one in the morning and one at bedtime.
Take the tablets on an empty stomach with a glass of water. Swallow them whole, and don't crush, chew or split them. This medicine should be taken every day, not just when you need it.
Side Effects
Drowsiness (somnolence) and other accidents can happen when Doxylamine Succinate and Pyridoxine Hydrochloride are taken together with CNS depressants.
Cautions & Contraindications
Warnings & Precautions
Doxylamine Succinate & Pyridoxine Hydrochloride can make a woman drowsy. This happens because Doxylamine Succinate is an antihistamine with anticholinergic properties. So women should avoid activities such as driving or operating heavy machinery while they are using it. It is also not recommended if a woman is taking central nervous system (CNS) depressants at the same time, and alcohol is one of these. Because of its anticholinergic properties, Doxylamine Succinate & Pyridoxine Hydrochloride should be used with caution in women with asthma, increased intraocular pressure, narrow angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction or urinary bladder-neck obstruction.
Contraindications
Doxylamine Succinate & Pyridoxine Hydrochloride must not be used by women who have any of the following conditions: a known hypersensitivity to Doxylamine Succinate, to other ethanolamine derivative antihistamines, to Pyridoxine Hydrochloride, or to any inactive ingredient in the formulation. It is also contraindicated with monoamine oxidase (MAO) inhibitors, because they intensify and prolong the adverse central nervous system effects of Doxylamine Succinate & Pyridoxine Hydrochloride.
Pregnancy & Breastfeeding
Pyridoxine Hydrochloride with Doxylamine Succinate is placed in pregnancy category A. It is meant for nausea and vomiting of pregnancy in women who haven't responded to conservative management. Both Doxylamine Succinate and Pyridoxine Hydrochloride pass into breast milk, so a breastfeeding mother should take care when using this medicine.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Doxylamine Succinate and Pyridoxine Hydrochloride comes as an extended-release or delayed-release formulation, so the signs of poisoning may not show straight away. In an overdose, a person may become restless and have a dry mouth, dilated pupils, sleepiness, vertigo, mental confusion and a fast heartbeat (tachycardia). At toxic doses, Doxylamine Succinate causes anticholinergic effects, and these include seizures, rhabdomyolysis, acute renal failure and death. If treatment is needed, it consists of gastric lavage or activated charcoal, whole bowel irrigation and symptomatic treatment.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep this medicine below 30°C, in a dry place away from light. Keep it out of reach of children.
Drug Interactions
Common questions about Emedox 20 mg+20 mg
What is Emedox 20 mg+20 mg Tablet (Extended Release)?
Emedox 20 mg+20 mg Tablet (Extended Release) is a medicine that contains Pyridoxine Hydrochloride + Doxylamine Succinate. It is made by Popular Pharmaceuticals PLC. It belongs to the Anti-emetic drugs group of medicines.
What is Emedox used for?
Emedox is used for: Nausea and Vomiting.
What are the side effects of Emedox?
Drowsiness (somnolence) and other accidents can happen when Doxylamine Succinate and Pyridoxine Hydrochloride are taken together with CNS depressants.
Can I take Emedox during pregnancy or while breastfeeding?
Pyridoxine Hydrochloride with Doxylamine Succinate is placed in pregnancy category A. It is meant for nausea and vomiting of pregnancy in women who haven't responded to conservative management. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Emedox?
Doxylamine Succinate and Pyridoxine Hydrochloride comes as an extended-release or delayed-release formulation, so the signs of poisoning may not show straight away. In an overdose, a person may become restless and have a dry mouth, dilated pupils, sleepiness, vertigo, mental confusion and a fast heartbeat (tachycardia). In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Emedox?
Keep this medicine below 30°C, in a dry place away from light. Keep it out of reach of children.
Can I take other medicines with Emedox?
Some medicines can interact with Pyridoxine Hydrochloride + Doxylamine Succinate, for example: Pyridoxine Hydrochloride, Doxylamine Succinate. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Doxrid DS by C2C Pharma Limited has the same ingredient and strength for ৳6.00 per unit, compared with ৳9.00 for Emedox. Ask your doctor or pharmacist before switching.
Do I need a prescription for Emedox?
Emedox is a prescription (Rx) medicine. Take it as your doctor advises.