Informational only — Not medical advice. Always consult a licensed healthcare provider.

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More from Desocort

Other strengths and forms by Incepta Pharmaceuticals Ltd.

Indications & Uses

Desoximetasone cream is used to relieve the inflammation and itching that come with skin conditions that respond to corticosteroids.

Pharmacology

Nobody knows exactly how topical steroids like desoximetasone reduce inflammation in steroid-responsive skin conditions. The usual explanation is that corticosteroids work by inducing proteins that inhibit phospholipase A2, which are together called lipocortins. First the drug binds to glucocorticoid receptors. The receptor then moves into the nucleus and binds to DNA, which switches various genes on and off.

These proteins are thought to control the making of strong inflammatory mediators such as prostaglandins and leukotrienes. They do this by blocking the release of arachidonic acid, the common precursor of both. Arachidonic acid is released from membrane phospholipids by phospholipase A2.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Put a thin film of Desoximetasone Cream on the affected areas of skin, twice a day, and rub it in gently.

Side Effects

Topical Desoximetasone can cause burning, itching, irritation and dryness of the skin. Other reported effects are folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis and allergic contact dermatitis. Maceration of the skin, skin atrophy, striae and miliaria have also been seen. These reactions are infrequent with Desoximetasone, but they may occur frequently when occlusive dressings are used.

Cautions & Contraindications

Warnings & Precautions

Desoximetasone is for use on the skin only. Keep it away from the eyes. Don't bandage, cover or wrap the treated area unless the doctor has told you to. If you notice any local side effects, especially under an airtight dressing, tell your doctor.

Contraindications

Desoximetasone cream must not be used by anyone who is known to be hypersensitive to Desoximetasone or to any of the other components in the preparation.

Pregnancy & Breastfeeding

No well-controlled studies of Desoximetasone have been done in pregnant women. So it should be used during pregnancy only if the likely benefit is greater than the possible risk to the baby. It isn't known whether Desoximetasone applied to the skin is absorbed into the body enough to appear in breast milk in a measurable amount. Even so, a nursing mother should use topical corticosteroids with caution.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Overdose

Desoximetasone Cream is not meant to be taken by mouth. If someone swallows it, get medical advice straight away. The patient should be watched closely, and supportive measures given as needed.

⚠️ In an emergency call 999 or go to the nearest hospital emergency department.

Storage

Store Desoximetasone at a temperature not above 30°C. Keep it away from light, and keep it out of the reach of children.

Common questions about Desocort 250 mg

What is Desocort 250 mg Cream?

Desocort 250 mg Cream is a medicine that contains Desoximetasone. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Other Topical corticosteroids group of medicines.

What is Desocort used for?

Desoximetasone cream is used to relieve the inflammation and itching that come with skin conditions that respond to corticosteroids.

What are the side effects of Desocort?

Topical Desoximetasone can cause burning, itching, irritation and dryness of the skin. Other reported effects are folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis and allergic contact dermatitis.

Can I take Desocort during pregnancy or while breastfeeding?

No well-controlled studies of Desoximetasone have been done in pregnant women. So it should be used during pregnancy only if the likely benefit is greater than the possible risk to the baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

What happens if I take too much Desocort?

Desoximetasone Cream is not meant to be taken by mouth. If someone swallows it, get medical advice straight away. In an emergency call 999 or go to the nearest hospital emergency department.

How should I store Desocort?

Store Desoximetasone at a temperature not above 30°C. Keep it away from light, and keep it out of the reach of children.

Do I need a prescription for Desocort?

Desocort is a prescription (Rx) medicine. Take it as your doctor advises.

Last updated: 15 Aug 2026