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Same active ingredient — pay up to 34% less
These brands contain the same active ingredient (Cefpodoxime Proxetil + Clavulanic Acid). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Combocef
Other strengths and forms by Advanced Chemical Industries PLC.
Indications & Uses
Combocef is indicated for:
Pharmacology
Cefpodoxime is a semi-synthetic, third generation cephalosporin. It works against several Gram positive and Gram negative microorganisms, and it stays stable in the presence of beta lactamase. Cefpodoxime is especially active against methicillin susceptible Staphylococci, Streptococcus pneumoniae, Haemophilus influenzae, Neisseria spp. and Moraxella catarrhalis.
Clavulanic acid is a natural beta lactamase inhibitor, produced by Streptomyces clavuligerus. It binds to beta lactamase moieties and inactivates them, so cefpodoxime is protected from being destroyed.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adults aged 12 years and older take Cefpodoxime Proxetil + Clavulanic Acid in these doses. In acute bacterial exacerbation of chronic bronchitis, it's 1 tablet every 12 hours for 10 days. Acute community acquired pneumonia needs 1 tablet every 12 hours for 14 days. For pharyngitis or tonsillitis, the dose is ½ tablet every 12 hours for 5 to 10 days. Skin and soft tissue infections are treated with 2 tablets every 12 hours for 7 to 14 days, and urinary tract infections with ½ tablet every 12 hours for 7 days. Uncomplicated gonorrhea needs a single dose. In acute maxillary sinusitis, take 1 tablet every 12 hours for 10 days. Children from 2 months to 12 years get 10 mg/kg/day in divided doses, every 12 hours.
Side Effects
Cefpodoxime is well tolerated by most people. The side effects seen most often affect the stomach and gut, and these are diarrhea, vomiting and abdominal pain.
Cautions & Contraindications
Warnings & Precautions
Take care when giving cefpodoxime to patients who are also being treated with diuretics.
Contraindications
Don't give Cefpodoxime to anyone who is known to be allergic to cephalosporins.
Pregnancy & Breastfeeding
Cefpodoxime and Clavulanic Acid falls under US FDA pregnancy category B. That said, there are no adequate and well-controlled studies in pregnant women. Animal reproduction studies don't always predict how a human will respond, so the medicine should be used during pregnancy only if it is clearly needed.
Cefpodoxime has been shown to pass into human milk. So caution should be exercised when Cefpodoxime is given to a nursing woman.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Store Cefpodoxime Proxetil + Clavulanic Acid in a dry place, away from light and heat. Keep it out of the reach of children.
Drug Interactions
Common questions about Combocef 100 mg+62.5 mg
What is Combocef 100 mg+62.5 mg Tablet?
Combocef 100 mg+62.5 mg Tablet is a medicine that contains Cefpodoxime Proxetil + Clavulanic Acid. It is made by Advanced Chemical Industries PLC. It belongs to the Third generation cephalosporins group of medicines.
What is Combocef used for?
Combocef is used for: Chronic Obstructive Pulmonary Disease, Pneumonia, Bronchitis, Sinusitis, Pharyngitis, Tonsillitis, Skin and Soft Tissue Infection.
What are the side effects of Combocef?
Cefpodoxime is well tolerated by most people. The side effects seen most often affect the stomach and gut, and these are diarrhea, vomiting and abdominal pain.
Can I take Combocef during pregnancy or while breastfeeding?
Cefpodoxime and Clavulanic Acid falls under US FDA pregnancy category B. That said, there are no adequate and well-controlled studies in pregnant women. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Combocef?
Store Cefpodoxime Proxetil + Clavulanic Acid in a dry place, away from light and heat. Keep it out of the reach of children.
Can I take other medicines with Combocef?
Some medicines can interact with Cefpodoxime Proxetil + Clavulanic Acid, for example: Cefpodoxime. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Xtabac by Opsonin Pharma Limited has the same ingredient and strength for ৳20.00 per unit, compared with ৳30.09 for Combocef. Ask your doctor or pharmacist before switching.
Do I need a prescription for Combocef?
Combocef is a prescription (Rx) medicine. Take it as your doctor advises.