Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Save on this medicine
Same active ingredient — pay up to 27% less
These brands contain the same active ingredient (Cefaclor Monohydrate). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Clorocef
Other strengths and forms by Ibn Sina Pharmaceutical Ind. Ltd.
Indications & Uses
Clorocef is indicated for:
Pharmacology
Cefaclor is a second generation cephalosporin antibiotic. It is stable against b-lactamase inactivation and has a broad spectrum of activity. In vitro, cefaclor is active against alpha and beta haemolytic Streptococci, Staphylococci (including coagulase-positive, coagulase negative and penicillinase-producing strains), Streptococcus pneumoniae, Streptococcus pyogenes (Group A b-haemolytic Streptococci), Branhamella catarrhalis, Escherichia coli, Proteus mirabilis, Klebsiella species and Haemophilus influenzae, including ampicillin-resistant strains. Cefaclor is generally effective in eradicating Streptococci from the nasopharynx.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual adult dose is 250 mg every 8 hours. For severe infections, or those caused by less susceptible organisms, the dose may be doubled, up to a maximum of 4 g/day. In β-hemolytic Streptococcal infections, therapy should be given for at least 10 days.
Dosage for other forms (1)
For paediatric patients over 1 month, the usual daily dose is 20 mg/kg/day, given in divided doses every 8 hours. In serious infections such as otitis media, and in infections caused by less susceptible organisms, 40 mg/kg/day is recommended, with a maximum of 1 g/day. Safety and effectiveness of Cefaclor in infants less than 1 month of age have not been established.
Under 1 year (9 kg): Powder for suspension, ½ tsp three times daily. Pediatric drops, 0.625 ml three times daily. For 1 to 5 years (9 kg to 18 kg): Powder for suspension, 1 tsp three times daily. Pediatric drops, 1.25 ml three times daily. Over 5 years: Powder for suspension, 2 tsp three times daily.
In renal impairment: Cefaclor may be given when kidney function is impaired. Dose adjustment is not usually required for patients with moderate or severe renal impairment.
In patients undergoing haemodialysis: Haemodialysis shortens the serum half-life by 25 to 30%. For these patients, a predialysis loading dose of 250 mg to 1 g is recommended. A maintaining dose of 250 to 500 mg every 6 hours may be used during the interdialytic period.
Geriatric use: Clinical experience hasn't shown any difference in response between elderly and younger patients, but greater sensitivity in some older people can't be ruled out.
Side Effects
Some patients taking Cefaclor Monohydrate (written as CFL in the source) may have stomach and bowel symptoms, such as diarrhea, nausea and vomiting. As with some penicillins and some other cephalosporins, transient hepatitis and cholestatic jaundice have been reported, though rarely. Fever, abdominal pain, superinfection, renal dysfunction, toxic nephropathy, hemorrhage, elevated LDH and pancytopenia may also occur with Cefaclor.
Cautions & Contraindications
Warnings & Precautions
Giving CFL (cefaclor) when there is no proven or strongly suspected bacterial infection, and no prophylactic indication, is unlikely to benefit the patient. It also raises the risk of drug-resistant bacteria developing. Prolonged use of CFL may lead to overgrowth of nonsusceptible organisms, and if superinfection occurs during therapy, appropriate measures should be taken. As with other β-lactam antibiotics, Probenecid inhibits the renal excretion of CFL. Antibiotics, including Cephalosporins, should be prescribed with caution in people with a history of gastrointestinal disease, particularly colitis. Before starting CFL, ask the patient carefully whether they have had hypersensitivity reactions to CFL, Cephalosporins, Penicillins or other drugs. Take caution if CFL is to be given to penicillin-sensitive patients. CFL should also be given cautiously to any patient who has shown some form of allergy, particularly to drugs.
Contraindications
Don't give Cefaclor to anyone who is known to be allergic to the cephalosporin group of antibiotics.
Pregnancy & Breastfeeding
No well-controlled studies have been done in pregnant women, so Cefaclor should be used during pregnancy only if it is clearly needed. Small amounts of Cefaclor have been found in breast milk. Nobody knows yet what effect this has on a nursing baby, so a nursing mother should take Cefaclor with caution.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
If someone takes too much Cefaclor Monohydrate, the signs of toxicity can include nausea, vomiting, epigastric distress and diarrhea.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Cefaclor Monohydrate at room temperature and away from light. Once the suspension has been reconstituted, you can use it within 7 days if it's kept at room temperature, or within 14 days if it's kept in a refrigerator (2 to 8°C). Always close the bottle tightly after use.
Drug Interactions
Common questions about Clorocef 250 mg
What is Clorocef 250 mg Capsule?
Clorocef 250 mg Capsule is a medicine that contains Cefaclor Monohydrate. It is made by Ibn Sina Pharmaceutical Ind. Ltd. It belongs to the Second generation cephalosporins group of medicines.
What is Clorocef used for?
Clorocef is used for: Pneumonia, Bronchitis, Pharyngitis, Tonsillitis, Urinary Tract Infection, Respiratory Tract Infection, Skin and Soft Tissue Infection, Otitis Media.
What are the side effects of Clorocef?
Some patients taking Cefaclor Monohydrate (written as CFL in the source) may have stomach and bowel symptoms, such as diarrhea, nausea and vomiting. As with some penicillins and some other cephalosporins, transient hepatitis and cholestatic jaundice have been reported, though rarely.
Can I take Clorocef during pregnancy or while breastfeeding?
No well-controlled studies have been done in pregnant women, so Cefaclor should be used during pregnancy only if it is clearly needed. Small amounts of Cefaclor have been found in breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Clorocef?
If someone takes too much Cefaclor Monohydrate, the signs of toxicity can include nausea, vomiting, epigastric distress and diarrhea. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Clorocef?
Keep Cefaclor Monohydrate at room temperature and away from light. Once the suspension has been reconstituted, you can use it within 7 days if it's kept at room temperature, or within 14 days if it's kept in a refrigerator (2 to 8°C).
Can I take other medicines with Clorocef?
Some medicines can interact with Cefaclor Monohydrate, for example: Warfarin Sodium. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Ceflon by Eskayef Pharmaceuticals Ltd. has the same ingredient and strength for ৳16.00 per unit, compared with ৳22.00 for Clorocef. Ask your doctor or pharmacist before switching.
Do I need a prescription for Clorocef?
Clorocef is a prescription (Rx) medicine. Take it as your doctor advises.