Pricing
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Clopramin is indicated for:
Pharmacology
Clomipramine Hydrochloride is an original tricyclic antidepressant and belongs to the dibenzazepine group of compounds. It is presumed to act on obsessive and compulsive behaviours through its effects on serotonergic neuronal transmission. The exact neurochemical mechanism isn't known. But the medicine can inhibit the reuptake of serotonin (5-HT), and this is thought to be important (as with obsessions and compulsions), which in turn hampers social acquaintance.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The initial dose of Clomipramine Hydrochloride is 25 mg at bedtime for about a week. After that the dose is raised gradually, but it should not go above 150 mg per day in adults and 75 mg per day in elderly patients. The dose can be given in divided form to reduce gastrointestinal disturbances. Clomipramine is not recommended for children.
Side Effects
The side effects people report most often with clomipramine hydrochloride are gastrointestinal disturbances, headache, dizziness, nausea, constipation and dry mouth. Increased sweating, shaking hands, tremor and difficulty in passing urine are also common. Some people have problems with their eyes, feel tired or sleepy, or notice sexual disturbance and restlessness.
Cautions & Contraindications
Warnings & Precautions
Talk to your doctor or pharmacist before taking Clomipramine Hydrochloride if you have ever had suicidal thoughts, suffer from epilepsy (fits), have had a head injury or have suffered brain damage, are going to have electric shock therapy (ECT), have other problems with your heart, have been told you have a low level of potassium in your blood (hypokalaemia, which the doctor will need to treat before you start taking clomipramine), have kidney disease, suffer from schizophrenia or other mental health conditions, have a blood disorder, have an overactive thyroid gland, have had severe constipation for a long time, have a tumour (cancer) of the adrenal gland (such as phaeochromocytoma or neuroblastoma), have liver disease, have low blood pressure, or wear contact lenses.
Contraindications
Clomipramine Hydrochloride should not be given to patients who have shown hypersensitivity to it, or to other tricyclic antidepressants belonging to the dibenzazepine group. It should also not be given to patients in the acute recovery phase following a myocardial infarction. And it should not be used with MAO (Monoamine Oxidase) inhibitors within 14 days.
Pregnancy & Breastfeeding
There are no adequate, well-controlled studies on the safety of clomipramine in pregnancy. Limited data suggest that clomipramine is likely to pass into human breast milk. It also has a known risk of damage to the fetus.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
Adults who have taken too much clomipramine hydrochloride have been reported to get a dry mouth, dilated pupils, coma and convulsions. Fast heartbeat (tachycardia) or an irregular heart rhythm (cardiac arrhythmia), slowed or weak breathing (respiratory depression) and changes in blood pressure have also been noted.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Clomipramine Hydrochloride below 30°C. Keep it away from light and out of the reach of children.
Drug Interactions
Common questions about Clopramin 25 mg
What is Clopramin 25 mg Tablet?
Clopramin 25 mg Tablet is a medicine that contains Clomipramine Hydrochloride. It is made by Incepta Pharmaceuticals Ltd. It belongs to the Tricyclic & related anti-depressant drugs group of medicines.
What is Clopramin used for?
Clopramin is used for: Depression.
What are the side effects of Clopramin?
The side effects people report most often with clomipramine hydrochloride are gastrointestinal disturbances, headache, dizziness, nausea, constipation and dry mouth. Increased sweating, shaking hands, tremor and difficulty in passing urine are also common.
Can I take Clopramin during pregnancy or while breastfeeding?
There are no adequate, well-controlled studies on the safety of clomipramine in pregnancy. Limited data suggest that clomipramine is likely to pass into human breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Clopramin?
Adults who have taken too much clomipramine hydrochloride have been reported to get a dry mouth, dilated pupils, coma and convulsions. Fast heartbeat (tachycardia) or an irregular heart rhythm (cardiac arrhythmia), slowed or weak breathing (respiratory depression) and changes in blood pressure have also been noted. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Clopramin?
Store Clomipramine Hydrochloride below 30°C. Keep it away from light and out of the reach of children.
Can I take other medicines with Clopramin?
Some medicines can interact with Clomipramine Hydrochloride, for example: Sertraline, Venlafaxine, Paroxetine, Fluoxetine, Furosemide, Armodafinil. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Clopramin is already among the lowest-priced brands of Clomipramine Hydrochloride at this strength.
Do I need a prescription for Clopramin?
Clopramin is a prescription (Rx) medicine. Take it as your doctor advises.