Indications & Uses
Bimator is indicated for:
Pharmacology
Bimatoprost is believed to lower intraocular pressure (IOP) in humans by increasing the outflow of aqueous humor through both the trabecular meshwork and the uveoscleral routes. It does this by mimicking a naturally occurring prostaglandin. Prostaglandins are a group of chemicals found in many places in the body, and in the eye they increase the drainage of aqueous humour out of the eyeball. Bimatoprost is a synthetic compound related to one of these natural prostaglandins, and it works by increasing that drainage. It may also lower the rate at which aqueous is formed in the eye. Both effects bring down the pressure inside the eye.
Timolol is a non-selective, beta-adrenergic receptor antagonist, similar to propranolol and nadolol. It does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity, but it does have a relatively high degree of lipid solubility. When timolol is applied to the eye, it reduces elevated intraocular pressure and also normal intraocular pressure, whether or not glaucoma is present. Elevated intraocular pressure is a major risk factor in the development of glaucomatous visual field loss and optic nerve damage.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
The usual dose of Bimatoprost + Timolol is one drop in the affected eye(s) once daily.
Pediatric use: Safety and effectiveness in pediatric patients have not been established.
Geriatric use: No overall differences in safety or effectiveness have been seen between elderly patients and other adult patients.
Side Effects
In clinical trials, ocular hyperemia (redness of the eye) was reported in approximately 26% of patients using Bimatoprost + Timolol. Other effects were seen in 5 to 10% of patients in these studies, and they included decreased visual acuity, eye discomfort, foreign body sensation, pain and pruritis.
Cautions & Contraindications
Warnings & Precautions
Bimatoprost + Timolol eye preparations are applied to the eye, but like other eye medicines of this kind, the active substances Timolol and Bimatoprost can be absorbed into the body. Timolol is a beta-blocker, so the same types of heart, lung and other adverse reactions seen with beta-blockers taken by mouth or injection may occur. Take care when treating patients who have severe, unstable or uncontrolled cardiovascular disease.
Contraindications
Don't use Bimatoprost + Timolol if you are known to be hypersensitive to any ingredient in this formulation.
Pregnancy & Breastfeeding
There isn't enough data on the use of the Bimatoprost / Timolol fixed combination in pregnant women. So it shouldn't be used during pregnancy unless it is clearly necessary.
Animal studies showed that Bimatoprost passes into rat's milk, and Timolol passes into human milk. For this reason, Bimatoprost / Timolol should not be used during breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Bimatoprost + Timolol below 25° C, in a dry place and away from light. Keep it out of reach of children. Once the bottle has been opened, the solution can be used for up to 28 days.
Common questions about Bimator 300 mcg
What is Bimator 300 mcg Eye Drops?
Bimator 300 mcg Eye Drops is a medicine that contains Bimatoprost + Timolol. It is made by Square Pharmaceuticals PLC, Gazipur. It belongs to the Other ophthalmic preparations group of medicines.
What is Bimator used for?
Bimator is used for: Hypertension, Glaucoma.
What are the side effects of Bimator?
In clinical trials, ocular hyperemia (redness of the eye) was reported in approximately 26% of patients using Bimatoprost + Timolol. Other effects were seen in 5 to 10% of patients in these studies, and they included decreased visual acuity, eye discomfort, foreign body sensation, pain and pruritis.
Can I take Bimator during pregnancy or while breastfeeding?
There isn't enough data on the use of the Bimatoprost / Timolol fixed combination in pregnant women. So it shouldn't be used during pregnancy unless it is clearly necessary. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Bimator?
Keep Bimatoprost + Timolol below 25° C, in a dry place and away from light. Keep it out of reach of children.
Do I need a prescription for Bimator?
Bimator is a prescription (Rx) medicine. Take it as your doctor advises.