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These brands contain the same active ingredient (Clopidogrel Bisulphate). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Anlet
Other strengths and forms by Globe Pharmaceuticals Ltd.
Indications & Uses
Anlet is indicated for:
Pharmacology
Clopidogrel is a prodrug, so the body has to convert it before it works. Its active metabolite binds irreversibly to the P2Y12 class of ADP receptors on platelets, and this stops platelets from being activated and clumping together. After single oral doses, dose-dependent inhibition of platelet aggregation can be seen at 2 hours. With repeated doses of 75 mg per day, clopidogrel inhibits ADP-induced platelet aggregation from the first day, and the inhibition reaches steady state between Day 3 and Day 7.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Acute Coronary Syndrome
When a patient needs an antiplatelet effect within hours, start clopidogrel with a single 300 mg (4 tablets) oral loading dose, then continue at 75 mg once daily. If you start without a loading dose, the antiplatelet effect takes several days longer to establish.
Recent MI, Recent Stroke, or Established Peripheral Arterial Disease
Give 75 mg once daily by mouth, without a loading dose.
Clopidogrel is taken orally, with or without food.
Side Effects
Clopidogrel Bisulphate is generally a well tolerated medicine. The common side effects are bleeding, diarrhoea, discomfort in the gastrointestinal tract, haemorrhage and skin reactions. Rare side effects include acquired haemophilia, anaemia, angioedema, arthralgia, arthritis and bone marrow disorders.
Cautions & Contraindications
Warnings & Precautions
Clopidogrel Bisulphate is a prodrug, so the body has to convert it to its active metabolite. Genetic variations in CYP2C19 (poor metabolizer) impair this conversion, and so do drugs that inhibit CYP2C19, such as Omeprazole and Esomeprazole. Using these drugs together with Clopidogrel Bisulphate, or giving it to a CYP2C19 poor metaboliser, may reduce its antiplatelet activity. Clopidogrel Bisulphate inhibits platelet aggregation for the lifetime of the platelet (7 to 10 days), so the risk of bleeding may increase. If platelet transfusion is used to restore hemostasis, it may be less effective when given within 4 hours of the loading dose or within 2 hours of the maintenance dose. Stopping Clopidogrel Bisulphate increases the risk of cardiovascular events. Before elective surgery that carries a major risk of bleeding, discontinue it 5 days beforehand. Restart it as soon as hemostasis is achieved. Thrombotic Thrombocytopenic Purpura (TTP) has been reported, and it needs urgent treatment, including plasmapheresis (plasma exchange). Hypersensitivity, including rash, angioedema or a hematologic reaction, has also been reported in patients receiving clopidogrel, and in those with a history of hypersensitivity to other thienopyridines.
Contraindications
Clopidogrel must not be given to anyone who is hypersensitive to the drug itself or to any other component of the product. It must also not be used when there is active pathological bleeding, such as a peptic ulcer or intracranial hemorrhage.
Pregnancy & Breastfeeding
No adequate and well-controlled studies have been done in pregnant women, so clopidogrel should be used during pregnancy only if it is clearly needed. It is not known whether clopidogrel passes into human breast milk. A decision has to be made either to stop breastfeeding or to stop the medicine, and that decision should take into account how important the medicine is for the mother.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Clopidogrel Bisulphate has not been shown to be safe or effective in children. In elderly patients, the dose doesn't need to be changed.
Overdose
Taking too much clopidogrel can cause bleeding problems. In theory, a platelet transfusion may help the blood clot normally again.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Clopidogrel Bisulphate below 30°C in a dry place. Keep it away from light and don't freeze it. Keep it out of the reach of children.
Drug Interactions
Common questions about Anlet 75 mg
What is Anlet 75 mg Tablet?
Anlet 75 mg Tablet is a medicine that contains Clopidogrel Bisulphate. It is made by Globe Pharmaceuticals Ltd. It belongs to the Anti-platelet drugs group of medicines.
What is Anlet used for?
Anlet is used for: Angina Pectoris, Myocardial Infarction, Stroke.
What are the side effects of Anlet?
Clopidogrel Bisulphate is generally a well tolerated medicine. The common side effects are bleeding, diarrhoea, discomfort in the gastrointestinal tract, haemorrhage and skin reactions.
Can I take Anlet during pregnancy or while breastfeeding?
No adequate and well-controlled studies have been done in pregnant women, so clopidogrel should be used during pregnancy only if it is clearly needed. It is not known whether clopidogrel passes into human breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Anlet?
Taking too much clopidogrel can cause bleeding problems. In theory, a platelet transfusion may help the blood clot normally again. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Anlet?
Store Clopidogrel Bisulphate below 30°C in a dry place. Keep it away from light and don't freeze it.
Can I take other medicines with Anlet?
Some medicines can interact with Clopidogrel Bisulphate, for example: Omeprazole, Repaglinide, Esomeprazole, Warfarin Sodium, Noradrenaline. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Flexiclot by Desh Pharmaceuticals Ltd. has the same ingredient and strength for ৳8.00 per unit, compared with ৳11.00 for Anlet. Ask your doctor or pharmacist before switching.
Do I need a prescription for Anlet?
Anlet is a prescription (Rx) medicine. Take it as your doctor advises.