Pricing
Prices are indicative MRP and may vary by pharmacy. Trend compares against the last recorded price.
All price changes →Indications & Uses
Aniducon is indicated for:
Pharmacology
Anidulafungin works by blocking glucan synthase, an enzyme found in fungal cells but not in mammalian cells. When this enzyme is blocked, the fungus can't make 1,3-β-D-glucan, which is an essential part of its cell wall.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Duration of treatment: there isn't enough data to support the 100 mg dose for longer than 35 days of treatment.
Patients with renal and hepatic impairment: no dose adjustment is needed for mild, moderate or severe hepatic impairment. No dose adjustment is needed for any degree of renal insufficiency either, including patients on dialysis.
Other special populations: adult patients need no dose adjustment based on gender, weight, ethnicity, HIV positivity or old age.
Candidemia and other forms of Candida infections
Adults get a 200 mg loading dose on Day 1, then 100 mg once daily as the maintenance dose for at least 14 days after the last positive culture. Pediatric patients (1 month of age and older) get a 3 mg/kg loading dose on Day 1 (not to exceed 200 mg), then 1.5 mg/kg once daily (not to exceed 100 mg) as the maintenance dose, also for at least 14 days after the last positive culture.
Esophageal Candidiasis
Adults get a 100 mg loading dose on Day 1, then 50 mg once daily as the maintenance dose for a minimum of 14 days and for at least 7 days after symptoms resolve. This use is not approved in pediatric patients.
Method of administration: Anidulafungin is for intravenous use only. Reconstitute it with water for injection to a concentration of 3.33 mg/mL, then dilute it further to a concentration of 0.77 mg/mL. The recommended rate of infusion should not exceed 1.1 mg/min (equivalent to 1.4 mL/min when reconstituted and diluted as instructed). Anidulafungin must not be given as a bolus injection.
Side Effects
The most common side effects of anidulafungin are low potassium in the blood (hypokalemia), nausea, vomiting, diarrhea, dyspepsia, abdominal pain, fever (pyrexia), insomnia, low blood pressure (hypotension), headache, anemia and thrombocytopenia.
Cautions & Contraindications
Warnings & Precautions
Hepatic Effects Anidulafungin can cause abnormal liver tests, hepatitis and hepatic failure, so hepatic function should be monitored during therapy. Hypersensitivity Anaphylaxis, including shock, has been reported. Infusion-related adverse reactions can also occur, possibly histamine-mediated, and these include rash, urticaria, flushing, pruritus, bronchospasm, dyspnea and hypotension. To reduce the chance of these reactions, don't exceed an infusion rate of 1.1 mg/minute. Risk of Neonatal Toxicity Associated with Polysorbates Anidulafungin contains polysorbate 80, an inactive ingredient. Thrombocytopenia, renal dysfunction, hepatomegaly, cholestasis, ascites, hypotension and metabolic acidosis have been reported in low-birth weight infants receiving high doses of polysorbate. The medicine is not approved in pediatric patients younger than 1 month of age. Hereditary Fructose Intolerance (HFI) Anidulafungin contains fructose. There is a risk of metabolic crisis with life-threatening hypoglycemia, hypophosphatemia, lactic acidosis and hepatic failure. Before giving Anidulafungin to pediatric patients, obtain a history of HFI symptoms.
Contraindications
Don't give Anidulafungin to anyone who is known to be allergic to it, including any of its ingredients. The same applies to people who are allergic to other echinocandins.
Pregnancy & Breastfeeding
We have no human data on Anidulafungin use in pregnant women, so it isn't known whether the medicine carries a risk of adverse developmental outcomes. There is also no data on whether Anidulafungin passes into human milk, what effect it may have on a breastfed infant, or whether it changes milk production.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Overdose
In clinical trials, one patient was given a single 400 mg dose of Anidulafungin by mistake as a loading dose. No clinical adverse events were reported.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep the unopened Anidulafungin vial in a refrigerator at 2-8°C. Don't freeze it.
Once the vial has been reconstituted, the solution can be stored at up to 25°C for up to 24 hours. Don't freeze it.
The infusion solution can be stored at up to 25°C for up to 48 hours. Don't freeze this one either.
Drug Interactions
Common questions about Aniducon 100 mg
What is Aniducon 100 mg IV Infusion?
Aniducon 100 mg IV Infusion is a medicine that contains Anidulafungin. It is made by Beacon Pharmaceuticals PLC. It belongs to the Candida infections group of medicines.
What is Aniducon used for?
Aniducon is used for: Fungal Infection.
What are the side effects of Aniducon?
The most common side effects of anidulafungin are low potassium in the blood (hypokalemia), nausea, vomiting, diarrhea, dyspepsia, abdominal pain, fever (pyrexia), insomnia, low blood pressure (hypotension), headache, anemia and thrombocytopenia.
Can I take Aniducon during pregnancy or while breastfeeding?
We have no human data on Anidulafungin use in pregnant women, so it isn't known whether the medicine carries a risk of adverse developmental outcomes. There is also no data on whether Anidulafungin passes into human milk, what effect it may have on a breastfed infant, or whether it changes milk production. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Aniducon?
In clinical trials, one patient was given a single 400 mg dose of Anidulafungin by mistake as a loading dose. No clinical adverse events were reported. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Aniducon?
Keep the unopened Anidulafungin vial in a refrigerator at 2-8°C. Don't freeze it.
Do I need a prescription for Aniducon?
Aniducon is a prescription (Rx) medicine. Take it as your doctor advises.