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Same active ingredient — pay up to 34% less
These brands contain the same active ingredient (Amlodipine Besilate + Valsartan). Same strength and form. Confirm the switch with your doctor or pharmacist.
More from Amlovas VS
Other strengths and forms by Popular Pharmaceuticals PLC
Indications & Uses
Amlodipine Besilate + Valsartan is used to treat hypertension. Because it is a fixed combination, it is not meant for starting treatment in someone who has not been treated for hypertension before.
Pharmacology
Amlodipine is a dihydropyridine calcium channel blocker. It stops calcium ions from moving into vascular smooth muscle and cardiac muscle. Valsartan works differently. It blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II by selectively stopping Angiotensin II from binding to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Because of this, its action does not depend on the pathways that make Angiotensin II.
Amlodipine and Valsartan have both been shown to lower blood pressure effectively. Each one does this by reducing peripheral resistance, but blocking calcium influx and reducing Angiotensin II vasoconstriction are complementary mechanisms.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Treatment of hypertension: Amlodipine works well for high blood pressure at once daily doses of 2.5 mg to 10 mg, and Valsartan works well at doses of 80 mg to 320 mg. In clinical trials of Amlodipine and Valsartan together, using amlodipine 5 mg to 10 mg with Valsartan 160 mg to 320 mg, the blood pressure lowering effect grew as the dose went up. Most of the effect is reached within 2 weeks of starting treatment or changing the dose. If needed, the dose can be raised after 1 to 2 weeks of treatment, up to a maximum of 10/320 mg once daily, to control blood pressure. Amlodipine Besilate + Valsartan can be taken with or without food, and it can be given together with other antihypertensive medicines. A patient whose blood pressure isn't properly controlled on Amlodipine alone or on Valsartan alone may be switched to this combination.
Elderly patients: Amlodipine is cleared more slowly in older people, so treatment should usually start at 2.5 mg.
Renal impairment: No change to the starting dose is needed in mild or moderate renal impairment. In severe renal impairment, increase the dose slowly.
Hepatic impairment: No change to the starting dose is needed in mild or moderate liver insufficiency. In hepatic impairment, increase the dose slowly.
Side Effects
The side effects of Amlodipine Besilate + Valsartan have generally been mild and short-lived. The most common ones are swelling of the legs and ankles (peripheral edema), a blocked nose, a sore throat with discomfort when swallowing, upper respiratory tract infection and dizziness, among others.
Cautions & Contraindications
Warnings & Precautions
Exposure of the fetus or newborn to Amlodipine Besilate + Valsartan should be avoided. Check the patient for hypotension. If a patient has severe obstructive coronary artery disease, warn them that there is a risk of myocardial infarction or increased angina. In patients with impaired hepatic function or severely impaired renal function, increase the dose slowly.
Contraindications
Amlodipine Besilate + Valsartan must not be given to anyone who is hypersensitive to any of the components in this combination product.
Pregnancy & Breastfeeding
Amlodipine Besilate + Valsartan is Pregnancy Category D. Nobody knows yet whether amlodipine or valsartan passes into human breast milk. Since the nursing infant could be harmed, the choice has to be made between stopping breastfeeding and stopping the medicine, and that choice should depend on how much the mother needs the medicine.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Amlodipine Besilate + Valsartan has not been shown to be safe or effective in children.
Storage
Store Amlodipine Besilate + Valsartan below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Common questions about Amlovas VS 5 mg+80 mg
What is Amlovas VS 5 mg+80 mg Tablet?
Amlovas VS 5 mg+80 mg Tablet is a medicine that contains Amlodipine Besilate + Valsartan. It is made by Popular Pharmaceuticals PLC. It belongs to the Combined antihypertensive preparations group of medicines.
What is Amlovas VS used for?
Amlodipine Besilate + Valsartan is used to treat hypertension. Because it is a fixed combination, it is not meant for starting treatment in someone who has not been treated for hypertension before.
What are the side effects of Amlovas VS?
The side effects of Amlodipine Besilate + Valsartan have generally been mild and short-lived. The most common ones are swelling of the legs and ankles (peripheral edema), a blocked nose, a sore throat with discomfort when swallowing, upper respiratory tract infection and dizziness, among others.
Can I take Amlovas VS during pregnancy or while breastfeeding?
Amlodipine Besilate + Valsartan is Pregnancy Category D. Nobody knows yet whether amlodipine or valsartan passes into human breast milk. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Amlovas VS?
Store Amlodipine Besilate + Valsartan below 30°C, and keep it away from light and moisture. Keep it out of the reach of children.
Is there a cheaper medicine with the same ingredient?
Amlosartan by Incepta Pharmaceuticals Ltd. has the same ingredient and strength for ৳6.00 per unit, compared with ৳9.03 for Amlovas VS. Ask your doctor or pharmacist before switching.
Do I need a prescription for Amlovas VS?
Amlovas VS is a prescription (Rx) medicine. Take it as your doctor advises.