Pricing
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All price changes →Indications & Uses
Aclene Plus is indicated for:
Pharmacology
Adapalene & Benzoyl peroxide gel is used to treat acne vulgaris (acne) in patients 12 years of age and older, applied to the skin. Adapalene attaches to specific retinoic acid receptors inside skin cells but does not attach to cytosolic receptor protein. Studies of its biochemical and pharmacological profile show that Adapalene helps regulate cell differentiation, keratinization, and inflammatory processes in the skin. By binding to these retinoic acid receptors, Adapalene helps normalize the differentiation of follicular epithelial cells, which reduces the formation of microcomedones (the earliest, tiny plugs that lead to acne lesions). Benzoyl peroxide works as an oxidizing agent with bacteria-killing and keratolytic (skin-peeling) effects.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Apply a thin layer of Adapalene & Benzoyl Peroxide gel once daily to the affected areas of the face and/or trunk, after washing. A pea-sized amount is usually enough to cover each area of the face (for example, the forehead, chin, or a cheek). Keep the gel away from the eyes, lips, and other mucous membranes, and do not use it orally, in the eyes, or vaginally.
Pediatric use: This medicine has not been established as safe or effective for children under 12 years of age.
Side Effects
Erythema, scaling, dryness, and a stinging or burning sensation can occur with use. The side effects reported most often are dry skin, contact dermatitis, and burning or irritation at the application site, along with general skin irritation.
Cautions & Contraindications
Warnings & Precautions
Avoid sun and sunlamp exposure; use sunscreen when sun exposure is unavoidable.
Contraindications
Should not be used by anyone who is hypersensitive to any of its ingredients.
Pregnancy & Breastfeeding
There are no well-controlled studies in pregnant women who have used adapalene and benzoyl peroxide together. Animal reproduction studies have also not been done with this combination gel or with benzoyl peroxide alone. Animal studies don't always predict what happens in people, so this medicine should be used during pregnancy only when the likely benefit outweighs the possible risk to the baby. It isn't known whether adapalene or benzoyl peroxide passes into breast milk after use, so care is needed when it's used by a woman who is breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Storage
Keep Adapalene + Benzoyl Peroxide in a cool, dry place, below 25°C, away from light and moisture. Close the tube tightly after each use. Keep it out of the reach of children.
Common questions about Aclene Plus 0.1%+2.5%
What is Aclene Plus 0.1%+2.5% Gel?
Aclene Plus 0.1%+2.5% Gel is a medicine that contains Adapalene + Benzoyl Peroxide. It is made by Drug International Unani Ltd. It belongs to the Topical retinoid and related preparations group of medicines.
What is Aclene Plus used for?
Aclene Plus is used for: Acne Vulgaris.
What are the side effects of Aclene Plus?
Erythema, scaling, dryness, and a stinging or burning sensation can occur with use. The side effects reported most often are dry skin, contact dermatitis, and burning or irritation at the application site, along with general skin irritation.
Can I take Aclene Plus during pregnancy or while breastfeeding?
There are no well-controlled studies in pregnant women who have used adapalene and benzoyl peroxide together. Animal reproduction studies have also not been done with this combination gel or with benzoyl peroxide alone. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
How should I store Aclene Plus?
Keep Adapalene + Benzoyl Peroxide in a cool, dry place, below 25°C, away from light and moisture. Close the tube tightly after each use.
Do I need a prescription for Aclene Plus?
Aclene Plus is a prescription (Rx) medicine. Take it as your doctor advises.