Save on this medicine
Other brands with the same active ingredient
These brands contain the same active ingredient (Voriconazole). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Vcand 200 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Oral-Voriconazole tablet and powder for suspension are to be taken at least one hour before or one hour following a meal: At or over 40 kg body weight: Loading dose regimen is 400 mg or 10 ml every 12 hours (for the first 24 hours) and maintenance dose (after first 24 hours) is 200 mg or 5 ml twice daily. Below 40 Kg body weight: Loading dose regimen is 200 mg or 5 ml every 12 hours (for the first 24 hours) and maintenance dose (after first 24 hours) is 100 mg or 2.5 ml twice daily. Or, as directed by the registered physician. Injection-Invasive Aspergillosisd: Loading dose: 6 mg/kg 12 hourly for the first 24 hours. Maintenance Dose: 4 mg/kg 12 hourly. Candidemia in nonneutropenic patients and other deep tissue Candida infections: Loading dose: 6 mg/kg 12 hourly for the first 24 hours. Maintenance Dose: 3-4 mg/kg 12 hourly. Scedosporiosis and Fusariosis: Loading dose: 6 mg/kg 12 hourly for the first 24 hours. Maintenance Dose: 4 mg/kg 12 hourly.
Side Effects
The most commonly reported side effects include abdominal pain, anemia, blurred vision, headache, chest pain, nausea, and diarrhea.
Cautions & Contraindications
Warnings & Precautions
Long-term use (whether for treatment or prophylaxis) beyond 180 days needs a careful weighing of benefits against risks. Cases of squamous cell carcinoma of the skin (SCC) have been reported in patients on prolonged Voritec therapy.
Contraindications
Known hypersensitivity to voriconazole or to any of its other ingredients. It should not be given together with terfenadine, astemizole, cisapride, pimozide, quinidine, or sirolimus, as this combination carries a risk of serious adverse reactions. It should also not be co-administered with rifampicin, carbamazepine, long-acting barbiturates, efavirenz, ritonavir, rifabutin, ergot alkaloids, or St. John's Wort, as these combinations risk reducing its effectiveness.