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Indications & Uses
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Detailed dosing reference is not available yet. Please follow your prescription and consult your pharmacist.
Side Effects
Azithromycin Dihydrate is well tolerated, and side-effects are uncommon. Most of the ones seen were mild to moderate in severity. The majority were gastrointestinal, with nausea, abdominal discomfort (pain or cramps), vomiting, flatulence, diarrhoea and loose stools being seen occasionally. Allergic reactions such as rash or photosensitivity have occurred, and there have also been rare reports of serious hypersensitivity reactions. Reversible rises in liver transaminases have been seen, at a frequency similar to that of the comparative macrolides and penicillins used in clinical trials. Cases of cholestatic jaundice have been observed rarely. Transient, mild reductions in neutrophil counts have occasionally been seen in clinical trials, although a causal relationship to azithromycin has not been established. Hearing impairment In investigational studies where higher doses were used for prolonged periods, reversible hearing impairment was seen in some patients.
Cautions & Contraindications
Warnings & Precautions
Rare but serious allergic reactions, including angioneurotic oedema and anaphylaxis, have been reported with erythromycin and other macrolides, and the same is true of azithromycin. In some people taking azithromycin, these reactions came back after the first episode. They needed a long period of observation and treatment.
Contraindications
Azithromycin Dihydrate must not be given to anyone who is hypersensitive to azithromycin or to any other macrolide antibiotic. It also must not be taken together with ergot derivatives. People with hepatic diseases should not use azithromycin either.
Pregnancy & Breastfeeding
Azithromycin Dihydrate falls under Pregnancy Category B. In animal reproduction studies, azithromycin showed no evidence of harm to the fetus. There are no adequate and well controlled studies in pregnant women, though. Animal studies don't always predict how humans will respond, so azithromycin should be used during pregnancy only if adequate alternatives are not available.
It is not known whether azithromycin is secreted in breast milk. For that reason, caution should be exercised when it is given to nursing women.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Use in renal impairment: People with mild renal impairment (creatinine clearance >40 ml/min) don't need a dose adjustment. There are no data on azithromycin in patients with more severe renal impairment, so take care when using azithromycin in these patients.
Use in hepatic impairment: The liver is the main route by which azithromycin leaves the body, so it should not be used in patients with hepatic disease.
Effects on ability to drive and use machines: There is no evidence that azithromycin affects a patient's ability to drive or operate machinery.
Overdose
There's no data on overdosage with Azithromycin Dihydrate. With macrolide antibiotics, the usual symptoms of overdosage are hearing loss, severe nausea, vomiting and diarrhoea. Gastric lavage and general supportive measures are indicated.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Store Azithromycin Dihydrate in a dry place, away from light and heat. Keep it where children can't reach it.
Drug Interactions
Common questions about Thromax 250 mg
What is Thromax 250 mg Tablet?
Thromax 250 mg Tablet is a medicine that contains Azithromycin Dihydrate. It is made by Novo Healthcare and Pharma Ltd. It belongs to the Macrolides group of medicines.
What is Thromax used for?
Thromax is used for: Pneumonia, Bronchitis, Sinusitis, Pharyngitis, Tonsillitis, Bacterial Infection, Respiratory Tract Infection, Skin and Soft Tissue Infection, Otitis Media.
What are the side effects of Thromax?
Azithromycin Dihydrate is well tolerated, and side-effects are uncommon. Most of the ones seen were mild to moderate in severity.
Can I take Thromax during pregnancy or while breastfeeding?
Azithromycin Dihydrate falls under Pregnancy Category B. In animal reproduction studies, azithromycin showed no evidence of harm to the fetus. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Thromax?
There's no data on overdosage with Azithromycin Dihydrate. With macrolide antibiotics, the usual symptoms of overdosage are hearing loss, severe nausea, vomiting and diarrhoea. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Thromax?
Store Azithromycin Dihydrate in a dry place, away from light and heat. Keep it where children can't reach it.
Can I take other medicines with Thromax?
Some medicines can interact with Azithromycin Dihydrate, for example: Cyclosporine, Azithromycin, Theophylline, Digoxin. Tell your doctor or pharmacist about every medicine you take.
Is there a cheaper medicine with the same ingredient?
Thromax is already among the lowest-priced brands of Azithromycin Dihydrate at this strength.
Do I need a prescription for Thromax?
Thromax is a prescription (Rx) medicine. Take it as your doctor advises.