Radiquin

Adults:

Hydroxychloroquine Sulphate tablets are taken by mouth, and it's best to take them with food to help avoid an upset stomach. For acute and chronic rheumatoid arthritis, the usual dose is 400 to 600 mg daily; once a good response is achieved, which is usually within 4 to 8 weeks, the dose can be reduced to 50%. For Systemic Lupus Erythematosus (SLE), the dose is 400 mg once or twice daily for several weeks or months depending on how the patient responds, with a maintenance dose of 200 to 400 mg daily. For malaria in adults, an initial dose of 800 mg is given, followed by 400 mg after 6 to 8 hours, and then 400 mg on each of the next two consecutive days. In children, a total dose equal to 25 mg/kg is given over 3 days as follows: the first dose is 10 mg base/kg, not exceeding a single dose of 620 mg base; the second dose is 5 mg base/kg, not exceeding a single dose of 310 mg base, given 6 hours after the first dose; the third dose is 5 mg base/kg given 18 hours after the second dose; and the fourth dose is 5 mg base/kg given 24 hours after the third dose.