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Other brands with the same active ingredient
These brands contain the same active ingredient (Prednisolone). Same strength and form. Confirm the switch with your doctor or pharmacist.
Indications & Uses
Pedlon 10 mg is indicated for:
Pharmacology
Prednisolone is a synthetic adrenocortical drug with predominantly glucocorticoid properties. It works by directly inhibiting the Phospholipase A2 enzyme, which is responsible for producing inflammatory mediators such as leukotrienes, SRS A, and prostaglandins. Taken orally, prednisolone is absorbed rapidly and well from the GI tract. In the plasma, it is 70 to 90% protein bound and has an elimination half life of 2 to 4 hours. It is metabolized mainly in the liver and excreted in the urine.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Adult Nephrotic Syndrome: Initial dose is 2 mg/kg/day (maximum 80 mg/day) in divided doses 3 to 4 times per day until the urine is protein free for 3 consecutive days (maximum 28 days), followed by 1 to 1.5 mg/kg/dose given every other day for 4 weeks. Maintenance dose: 0.5 to 1 mg/kg/dose given every other day for 3 to 6 months. Anti-inflammatory: 5 to 60 mg per day in divided doses 1 to 4 times per day. Acute Asthma: 40 to 60 mg/day PO as a single daily dose or divided every 12 hours for 3 to 10 days. Allergic Conditions: Day 1: 10 mg PO before breakfast, 5 mg after lunch and after dinner, and 10 mg at bedtime. Day 2: 5 mg PO before breakfast, after lunch, and after dinner, and 10 mg at bedtime. Day 3: 5 mg PO before breakfast, after lunch, after dinner, and at bedtime. Day 4: 5 mg PO before breakfast, after lunch, and at bedtime. Day 5: 5 mg PO before breakfast and at bedtime. Day 6: 5 mg PO before breakfast. Pediatric Asthma: Under 1 year: Acute: 10 mg orally every 12 hours. Maintenance: 10 mg orally every other day. 1 to 4 years: Acute: 20 mg orally every 12 hours. Maintenance: 20 mg orally every other day. 5 to 12 years: Acute: 30 mg orally every 12 hours. Maintenance: 30 mg orally every other day. Over 12 years: Acute: 40 mg orally every 12 hours. Maintenance: 40 mg orally every other day. Anti-inflammatory: 0.05 to 2 mg/kg/day divided into 1 to 4 doses per day. Immunosuppression: 0.05 to 2 mg/kg/day divided into 1 to 4 doses per day.
Side Effects
Fluid and Electrolyte Disturbances: the medicine can cause the body to retain sodium and fluid, which may lead to congestive heart failure in patients who are prone to it; it can also cause potassium loss, hypokalemic alkalosis, and hypertension. Musculoskeletal: it may cause muscle weakness, steroid myopathy, and loss of muscle mass, as well as osteoporosis, vertebral compression fractures, aseptic necrosis of the femoral and humeral heads, and pathologic fractures of long bones. Gastrointestinal: it can cause peptic ulcer with a possible risk of perforation and bleeding, pancreatitis, abdominal distension, and ulcerative esophagitis. Dermatologic: it may impair wound healing and cause thin, fragile skin, petechiae and bruising (ecchymoses), facial redness, and increased sweating, and it may suppress reactions to skin tests. Neurological: it can cause convulsions and, usually after treatment has stopped, increased pressure inside the skull with swelling of the optic disc (cerebral pseudo-tumor), along with vertigo and headache. Endocrine: it may cause menstrual irregularities, a Cushingoid appearance, and suppressed growth in children, as well as secondary unresponsiveness of the adrenal cortex and pituitary gland, particularly during periods of stress such as trauma, surgery, or illness; it can also reduce carbohydrate tolerance, bring out latent diabetes mellitus, and increase the insulin or oral hypoglycemic dose needed by diabetic patients. Ophthalmic: it may cause posterior subcapsular cataracts, raised pressure within the eye, glaucoma, and bulging of the eyes (exophthalmos). Metabolic: it can cause a negative nitrogen balance due to the breakdown of protein.
Cautions & Contraindications
Warnings & Precautions
Anyone taking high, immunosuppressant doses of corticosteroids should be told to avoid contact with chickenpox or measles. If they do come into contact with either, they should see a doctor straight away. When a patient on corticosteroids goes through unusual stress, a higher dose of a rapidly acting corticosteroid may be needed. This applies before, during and after the stressful situation. Corticosteroids can hide some signs of infection, and new infections may develop while a person is taking them. Resistance to infection may drop, and it can become hard to tell where an infection is. Long-term use can cause posterior subcapsular cataracts and glaucoma, which may damage the optic nerves. It can also make it easier for secondary eye infections caused by fungi or viruses to take hold. Average and large doses of hydrocortisone or cortisone can raise blood pressure, cause the body to hold on to salt and water, and increase the amount of potassium lost in urine. A patient on corticosteroid therapy should not be vaccinated against smallpox. Other vaccinations should also be avoided in people taking corticosteroids, especially high doses, as there is a risk of neurological complications and the body may not build a proper antibody response. Children taking medicines that suppress the immune system are more likely to catch infections than healthy children. In children who have no immunity, or in adults on corticosteroids, chickenpox and measles can be much more serious and, in some cases, fatal.
Contraindications
Contraindicated in systemic infections not covered by specific anti-infective therapy, known hypersensitivity to any ingredient, and ocular herpes simplex due to the risk of perforation.
Pregnancy & Breastfeeding
Not recommended for use during pregnancy unless your doctor considers it essential. It should be used only if the expected benefit to the mother clearly outweighs any possible risk to the unborn baby. Corticosteroids do pass into breast milk and may slow the baby's growth, affect the body's own natural corticosteroid production, or cause other unwanted effects.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Use in Special Populations
Pediatric use: ln the treatment of endocrine disorders such as primary and secondary adrenocortical insufficiency in infancy, mineralocorticoid supplementation is of particular importance. lnfants born to mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism. lmmunization procedures should not be undertaken in patients who are on corticosteroids. Pediatric patients who are on drugs which suppress the immune system are more susceptible to infections than healthy pediatric patients. Chickenpox and measles, for example, can have more serious or even fatal course in non-immune patients on corticosteroids. Growth and development in pediatric population on prolonged corticosteroid therapy should be carefully observed. See contraindications and warnings for complete information.
Overdose
Adverse effects related to prednisone normally develop only after prolonged use of doses in excess of the normal physiological requirement. Treatment is symptomatic and where possible the prednisone dose should be reduced gradually.
⚠️ In an emergency call 999 or go to the nearest hospital emergency department.
Storage
Keep Prednisolone in a cool, dry place and away from light. Make sure children can't reach it.
Drug Interactions
Common questions about Pedlon 10 mg 10 mg
What is Pedlon 10 mg 10 mg Tablet?
Pedlon 10 mg 10 mg Tablet is a medicine that contains Prednisolone. It is made by MST Pharma and Healthcare Ltd. It belongs to the Glucocorticoids group of medicines.
What is Pedlon 10 mg used for?
Pedlon 10 mg is used for: Osteoarthritis, Rheumatoid Arthritis.
What are the side effects of Pedlon 10 mg?
Fluid and Electrolyte Disturbances: the medicine can cause the body to retain sodium and fluid, which may lead to congestive heart failure in patients who are prone to it; it can also cause potassium loss, hypokalemic alkalosis, and hypertension. Musculoskeletal: it may cause muscle weakness, steroid myopathy, and loss of muscle mass, as well as osteoporosis, vertebral compression fractures, aseptic necrosis of the femoral and humeral heads, and pathologic fractures of long bones.
Can I take Pedlon 10 mg during pregnancy or while breastfeeding?
Not recommended for use during pregnancy unless your doctor considers it essential. It should be used only if the expected benefit to the mother clearly outweighs any possible risk to the unborn baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
What happens if I take too much Pedlon 10 mg?
Adverse effects related to prednisone normally develop only after prolonged use of doses in excess of the normal physiological requirement. Treatment is symptomatic and where possible the prednisone dose should be reduced gradually. In an emergency call 999 or go to the nearest hospital emergency department.
How should I store Pedlon 10 mg?
Keep Prednisolone in a cool, dry place and away from light. Make sure children can't reach it.
Can I take other medicines with Pedlon 10 mg?
Some medicines can interact with Prednisolone, for example: Magaldrate + Simethicone, Montelukast Sodium, Carbamazepine, Griseofulvin, Primidone, Phenytoin. Tell your doctor or pharmacist about every medicine you take.
Do I need a prescription for Pedlon 10 mg?
Pedlon 10 mg is a prescription (Rx) medicine. Take it as your doctor advises.