Indications & Uses
Panalon is used alongside general anesthesia during surgery. It helps relax the skeletal muscles and makes it easier to insert a breathing tube into the windpipe, and its effect is suited to operations of medium to long duration.
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Facilitate endotracheal intubation, Muscle relaxant in general anaesthesia: Adult: Initially, 50-100 mcg/kg by inj, may reduce to 20-60 mcg/kg if given after suxamethonium. Maintenance: 10-20 mcg/kg. Child: 0-30 days Initially, 30-40 mcg/kg. Maintenance: 10-20 mcg/kg; >1 mth Same as adult dose. Facilitate mechanical ventilation in intensive care: Adult: 60 mcg/kg every 1-1.5 hr or less frequently.
Side Effects
Tachycardia, HTN, bradycardia, bronchospasm, hypotension, CV collapse, excessive salivation; pain or local skin reactions at inj site. Rarely, hypersensitivity reactions.
Cautions & Contraindications
Warnings & Precautions
Use with caution in patients with burn injury, biliary tract disease, pulmonary disease, muscular dystrophies, myasthenia gravis, myasthenic syndrome, electrolyte disturbance, altered blood pH, dehydration, CV (cardiovascular) disease, oedema, raised catecholamine concentration, and those at risk of HTN (hypertension). Also use cautiously in renal and hepatic impairment, in children, and during pregnancy and lactation.
Contraindications
Pancuronium should not be given to patients who are hypersensitive to it or to the bromide ion.