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Other brands with the same active ingredient
These brands contain the same active ingredient (Nitroglycerin). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Pactorin is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Sublingual tablet: One tablet (0.5 mg) should be dissolved under the tongue as soon as an acute anginal attack begins. The dose may be repeated about every five minutes until relief is obtained. If pain continues after a total of 3 tablets taken within 15 minutes, prompt medical attention is recommended. Sustained release tablet: The dose should always be adjusted according to the individual patient's requirement, response and the severity of the anginal pain. 2.6 mg: 1 tablet 2 times a day before meals, in the morning and at noon. If necessary, the dose may be raised gradually to 2 or 3 tablets twice daily. 6.4 mg: One tablet twice daily, or as directed by the registered physician. Spray: At the onset of an attack, one metered dose spray or two metered dose sprays should be given under the tongue. A spray may be repeated about every 5 minutes as needed, up to a maximum of 3 metered sprays within a 15 minute period. If chest pain continues after a total of 3 sprays, prompt medical attention is recommended. It may also be used beforehand, 5 to 10 minutes ahead of activities that might bring on an acute attack.
Side Effects
The most common side effects are headache, flushing, and low blood pressure.
Cautions & Contraindications
Warnings & Precautions
Nitrofix SR works best at the lowest dose that relieves the acute anginal attack; using more than needed raises the risk of tolerance developing. It should be used cautiously in patients who are, or may already be, volume-depleted or hypotensive.
Contraindications
Contraindicated in patients using PDE5 inhibitors (sildenafil, vardenafil, or tadalafil), as well as those with severe anemia, raised intracranial pressure, hypersensitivity to nitroglycerin or other nitrates/nitrites, or acute circulatory failure (shock).