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Ornid -500

Rx

500 mg • Tablet

Ornidazole • Drug International Ltd., Gopalpur

Therapeutic class: Amoebicides

🌐 বাংলায় দেখুন

Available as: 500 mg

Indications & Uses

Ornid -500 is indicated for:

Pharmacology

Ornidazole belongs to the 5-nitroimidazole class of medicines and works against both protozoa and anaerobic bacteria. Inside susceptible organisms, it is broken down into reduction products that attack the DNA, damaging its helical structure and breaking its strands. This disruption stops the organism from making the proteins it needs to survive, ultimately killing the cell.

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Amoebiasis: Adults take 500 mg twice a day for 5 days. Children take 10 to 25 mg per kg of body weight, given in two divided doses.

Amoebic dysentery: Adults take 1500 mg once a day for 3 days. Children take 40 mg per kg of body weight once a day for 3 days.

Giardiasis: Adults take 1500 mg once daily for 1 to 2 days. Children take 40 mg per kg of body weight for 2 days.

Trichomoniasis: 1500 mg as a single dose, or 500 mg twice a day for 5 days. The sexual partner should be treated at the same time.

Bacterial vaginosis: 3 tablets of 500 mg each taken as a single dose, or one 500 mg tablet once daily for 5 to 7 days.

Side Effects

Side effects of Ornil have mostly been confined to the gastrointestinal tract (nausea, vomiting, epigastric pain) and the central nervous system (dizziness, headache, lassitude). Unlike other nitroimidazoles, Ornil does not interact with alcohol, although this requires further study. Leukopenia has occasionally been described during therapy. Adverse central nervous system (CNS) effects of Ornil have mainly included headache, dizziness, lassitude or somnolence, fatigue and weakness. Adverse CNS effects of Ornil may be fewer than those seen with metronidazole. Seizures have not been reported with Ornil in the studies available to date.

Cautions & Contraindications

Warnings & Precautions

Ornil should be prescribed with caution in patients with ataxia, vertigo, or mental confusion. During prolonged treatment with Ornil, blood dyscrasias, namely mild leukopenia, have rarely been reported. If leukopenia occurs, the decision to discontinue therapy should depend on the severity of the infection.

Contraindications

Ornidazole should not be used by anyone who has had an allergic reaction to it or to other nitroimidazoles. It is also contraindicated in people with central nervous system disorders, especially epilepsy or peripheral neuropathy.

Pregnancy & Breastfeeding

There haven't been enough clinical trials of Ornidazole in pregnancy or during breastfeeding. For that reason, a doctor should prescribe it only when the likely benefit is greater than the possible risk to the fetus or the newborn baby.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Use in Special Populations

Renal impairment

For patients on haemodialysis, give a supplemental dose of Ornidazole before dialysis. This should be 50% of the usual dose.

Hepatic impairment

In severe hepatic impairment, double the interval between doses.

Storage

Store at room temperature and protect from light and moisture.

Drug Interactions

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Moderate Fluorouracil

Common questions about Ornid -500 500 mg

What is Ornid -500 500 mg Tablet?

Ornid -500 500 mg Tablet is a medicine that contains Ornidazole. It is made by Drug International Ltd., Gopalpur. It belongs to the Amoebicides group of medicines.

What is Ornid -500 used for?

Ornid -500 is used for: Amoebiasis, Giardiasis.

What are the side effects of Ornid -500?

Side effects of Ornil have mostly been confined to the gastrointestinal tract (nausea, vomiting, epigastric pain) and the central nervous system (dizziness, headache, lassitude). Unlike other nitroimidazoles, Ornil does not interact with alcohol, although this requires further study.

Can I take Ornid -500 during pregnancy or while breastfeeding?

There haven't been enough clinical trials of Ornidazole in pregnancy or during breastfeeding. For that reason, a doctor should prescribe it only when the likely benefit is greater than the possible risk to the fetus or the newborn baby. Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

How should I store Ornid -500?