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Other brands with the same active ingredient
These brands contain the same active ingredient (Ornidazole). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
OR-500 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Amoebiasis: Adults take 500 mg twice a day for 5 days. Children take 10 to 25 mg per kg of body weight, given in two divided doses. Amoebic dysentery: Adults take 1500 mg once a day for 3 days. Children take 40 mg per kg of body weight once a day for 3 days. Giardiasis: Adults take 1500 mg once daily for 1 to 2 days. Children take 40 mg per kg of body weight for 2 days. Trichomoniasis: 1500 mg as a single dose, or 500 mg twice a day for 5 days. The sexual partner should be treated at the same time. Bacterial vaginosis: 3 tablets of 500 mg each taken as a single dose, or one 500 mg tablet once daily for 5 to 7 days.
Side Effects
Side effects of Ornil have mostly been confined to the gastrointestinal tract (nausea, vomiting, epigastric pain) and the central nervous system (dizziness, headache, lassitude). Unlike other nitroimidazoles, Ornil does not interact with alcohol, although this requires further study. Leukopenia has occasionally been described during therapy. Adverse central nervous system (CNS) effects of Ornil have mainly included headache, dizziness, lassitude or somnolence, fatigue and weakness. Adverse CNS effects of Ornil may be fewer than those seen with metronidazole. Seizures have not been reported with Ornil in the studies available to date.
Cautions & Contraindications
Warnings & Precautions
Ornil should be prescribed with caution in patients with ataxia, vertigo, or mental confusion. During prolonged treatment with Ornil, blood dyscrasias, namely mild leukopenia, have rarely been reported. If leukopenia occurs, the decision to discontinue therapy should depend on the severity of the infection.
Contraindications
Ornidazole should not be used by anyone who has had an allergic reaction to it or to other nitroimidazoles. It is also contraindicated in people with central nervous system disorders, especially epilepsy or peripheral neuropathy.