Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago
Available as: 0.5%+0.3% · 5 ml drop 0.5%+0.3% 0.5%+0.3% 0.5%+0.3%

Indications & Uses

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Shake the bottle well before each use. Place one drop into the conjunctival sac (the pocket between the lower lid and the eye) of the affected eye or eyes every four to six hours. During the first 24 to 48 hours of treatment, the frequency may be increased to one drop every one to two hours.

Side Effects

Possible side effects include raised pressure inside the eye, burning or stinging when the drops are put in, vision problems, eye discharge, itching, abnormal tearing, sensitivity to light, deposits on the cornea, eye discomfort, eyelid problems, and other unspecified eye disorders. Headache, a side effect not affecting the eye, has also been reported.

Cautions & Contraindications

Warnings & Precautions

Patients should be re-evaluated if their signs and symptoms do not improve after two days of treatment. Intraocular pressure should be monitored in anyone using Lotepin T for 10 days or longer. Where a steroid has been used or is still in use, fungal invasion must be considered in any corneal ulceration that persists. Patients should be advised to consult a physician if redness or itching worsens. Those who wear soft contact lenses and whose eyes are not red should wait at least ten minutes after instilling the product before inserting their lenses.

Contraindications

Like other steroid and anti-infective eye drop combinations, Loteprednol Etabonate & Tobramycin must not be used in most viral infections of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia and varicella. It must also not be used in mycobacterial infections of the eye or fungal infections of the eye's structures. It is also not suitable for anyone with a known or suspected allergy to any ingredient in this preparation or to other corticosteroids.

Drug Interactions

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Last updated: 20 Aug 2026