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Other brands with the same active ingredient

These brands contain the same active ingredient (Phenytoin Sodium). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.

Indications & Uses

Epitoin is indicated for:

Dosage Reference

Reference Information Only

Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.

Adults:

Adults: The starting dose is 200 mg (2 tablets) daily, increased to 400 mg daily in divided doses, up to a maximum of 600 mg per day. Alternatively, 3 to 4 mg/kg daily may be given in divided doses. For adults who have not received any previous medication, the usual treatment is one tablet three times daily, or as directed by the physician. Children: The initial dose is 5 mg/kg per day, given in two or three equally divided doses. The dose is then adjusted for the individual child, up to a maximum of 300 mg daily. The recommended daily maintenance dose is usually 4 to 8 mg/kg. Children over 6 years of age require the minimum adult dose of 300 mg per day.

Side Effects

Skin rashes occasionally develop during treatment, but they clear once the medicine is stopped. Treatment can then be restarted at a lower dose. Other possible side effects include insomnia, slurred speech, short-lived nervousness, dizziness and headache.

Cautions & Contraindications

Warnings & Precautions

During long-term treatment, periodic blood tests are advisable. Treatment should be stopped if a skin rash appears. Hyperglycaemia has been reported, resulting from the drug's inhibitory effect on insulin release. Phenytoin should be used with caution in pregnancy and in breastfeeding mothers.

Contraindications

Phenytoin should not be used in patients who are hypersensitive to phenytoin or to other hydantoins.

Drug Interactions

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Last updated: 15 Aug 2026