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Other brands with the same active ingredient
These brands contain the same active ingredient (Glibenclamide). Strength and form may differ — confirm substitution with your doctor or pharmacist before switching.
Indications & Uses
Diamide is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
There is no single fixed dosage schedule for treating diabetes mellitus with Glibenclamide or with any other hypoglycemic medicine. As initial therapy, the usual starting dose is 2.5 to 5 mg daily, taken with breakfast or the first main meal of the day. Those patients who may be more sensitive to hypoglycemic drugs should begin at a lower dose of 1.25 mg daily. The usual maintenance dose falls in the range of 1.25 to 20 mg daily, and this may be taken as a single dose or split into divided doses. Any increase in dosage should be made in steps of no more than 2.5 mg, spaced at least a week apart, guided by the patient's blood glucose response. Daily doses above 20 mg are not recommended.
Side Effects
Severe hypoglycemic reactions involving coma, seizure, or other neurological impairment occur infrequently.
Cautions & Contraindications
Warnings & Precautions
All sulfonylureas, including glibenclamide, can cause severe hypoglycaemia (low blood sugar). To reduce the risk of hypoglycaemic episodes, it is important to select suitable patients, use the correct dose, and give clear instructions.
Contraindications
Glibenclamide should not be used by people who are known to be allergic to the drug or to any of its other ingredients. It is also not suitable for people with type 1 diabetes or for those who have diabetic ketoacidosis, whether or not they are in a coma. Such conditions need to be treated with insulin instead.