Indications & Uses
Amisys 100 is indicated for:
Dosage Reference
Reference Information Only
Dosages shown are general references from official sources. Always consult your doctor or pharmacist for personalized dosing.
Adults:
Dosage Adults and children: 15 mg/kg/day given in two equally divided doses (equivalent to 500 mg twice daily in adults). The 100 mg strength is recommended for children so that the appropriate dose can be measured accurately. Neonates and premature infants: An initial loading dose of 10 mg/kg, followed by 15 mg/kg/day in two equally divided doses. Elderly: Amikacin is excreted by the renal route. Renal function should be assessed whenever possible, and the dosage adjusted as described under impaired renal function. Life threatening infections and/or those caused by Pseudomonas: The adult dose may be increased to 500 mg every eight hours, but should neither exceed 1.5 g/day nor be given for longer than 10 days. A maximum total adult dose of 15 g should not be exceeded. Urinary tract infections (other than pseudomonal infections): 7.5 mg/kg/day in two equally divided doses (equivalent to 250 mg twice daily in adults). Impaired renal function: In patients with impaired renal function, the daily dose should be reduced and/or the interval between doses increased to avoid accumulation of the drug.
Side Effects
The adverse effects have been reported with the use of Amikin are tinnitus, vertigo, partial reversible or irreversible deafness, skin rash, drug fever, headache, paraesthesia, nausea and vomiting.
Cautions & Contraindications
Warnings & Precautions
Because Amikin reaches high concentrations in the renal excretory system, patients should be kept well hydrated to help minimize chemical irritation of the renal tubules. If azotemia worsens, treatment should be discontinued. Monitoring renal function throughout treatment with aminoglycosides such as Amikin is especially important.
Contraindications
Amikacin Injection should not be used in patients who are known to be hypersensitive to Amikacin or to any of the other ingredients in the injection.