Verapamil Hydrochloride

ইঙ্গিত

Hypertension Angina Pectoris Cardiac Arrhythmia

Veramil SR Tablet is used for essential hypertension, angina pectoris and prevention of re-infarction, and supraventricular arrhythmias. Veramil SR Injection is used for tachycardias such as paroxysmal supraventricular tachycardias, atrial fibrillation with rapid ventricular response (except WPWS), atrial flutter with rapid conduction, and extrasystoles, as well as acute hypertension and acute coronary insufficiency. It is also used for the prophylaxis and/or therapy of ectopic arrhythmias (predominantly ventricular extrasystoles) in halothane anaesthesia, and in the application of adrenaline in halothane anaesthesia respectively.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Verapamil is an L-type calcium channel blocker with antiarrhythmic, antianginal, and antihypertensive effects. The immediate-release form wears off relatively quickly, so it needs to be taken 3 to 4 times a day, whereas extended-release formulations act longer and can be taken just once daily. Because verapamil reduces the force of the heart's contractions (a negative inotropic effect), it should be avoided in patients with severe left ventricular dysfunction or hypertrophic cardiomyopathy, since this weakening of contractility could worsen these existing conditions.

Pregnancy & Breastfeeding

Verapamil hasn't been thoroughly studied in pregnant women, so doctors generally reserve it for cases where it's clearly necessary. The drug does cross the placenta and can be found in umbilical vein blood at the time of delivery. It also passes into breast milk, which is why breastfeeding is usually stopped for as long as Verapamil treatment continues.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Verapamil Tablet: The dose of Verapamil should be individualized by titration, and the drug should be taken with food. For essential hypertension, the initial dose is 180 mg in the morning. If an adequate response is not obtained with 180 mg of Verapamil, the dose may be titrated in the following manner: 240 mg each morning; 180 mg each morning plus 180 mg each evening; or 240 mg every 12 hours. For angina, the usual dose is 80 mg to 120 mg three times a day. For arrhythmias in digitalized patients, Verapamil should be given at 240 mg to 360 mg in divided doses, depending on the severity of the condition. Divided doses of up to 180 mg a day may occasionally be needed. Verapamil Injection: Adults: 5 mg slowly by intravenous injection for tachycardias and hypertensive crises, repeated after 5 to 10 minutes if necessary. As a drip infusion to maintain the therapeutic effect, 5 to 10 mg an hour in physiological saline, glucose, laevulose or similar solutions, up to an average total dose of 100 mg a day. Children: newborns, 0.75 to 1 mg (0.3 to 0.4 ml); infants, 0.75 to 2 mg (0.3 to 0.8 ml); children aged 1 to 5 years, 2 to 3 mg (0.8 to 1.2 ml); and children aged 6 to 14 years, 2.5 to 5 mg (1 to 2 ml) of Verapamil, given intravenously depending on age and response. The injection should be given slowly under electrocardiographic control and only until the effect begins. For intravenous infusion in hypertensive crises, the initial dose is 0.05 to 0.1 mg/kg an hour; if the effect proves insufficient, the dose is increased at 30 to 60 minute intervals until twice the dose or more is reached, up to an average total dose of 1.5 mg/kg a day.

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No side-effect data recorded yet.

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