VERAMIL 180

Adults:

Verapamil Tablet: The dose of Verapamil should be individualized by titration, and the drug should be taken with food. For essential hypertension, the initial dose is 180 mg in the morning. If an adequate response is not obtained with 180 mg of Verapamil, the dose may be titrated in the following manner: 240 mg each morning; 180 mg each morning plus 180 mg each evening; or 240 mg every 12 hours. For angina, the usual dose is 80 mg to 120 mg three times a day. For arrhythmias in digitalized patients, Verapamil should be given at 240 mg to 360 mg in divided doses, depending on the severity of the condition. Divided doses of up to 180 mg a day may occasionally be needed. Verapamil Injection: Adults: 5 mg slowly by intravenous injection for tachycardias and hypertensive crises, repeated after 5 to 10 minutes if necessary. As a drip infusion to maintain the therapeutic effect, 5 to 10 mg an hour in physiological saline, glucose, laevulose or similar solutions, up to an average total dose of 100 mg a day. Children: newborns, 0.75 to 1 mg (0.3 to 0.4 ml); infants, 0.75 to 2 mg (0.3 to 0.8 ml); children aged 1 to 5 years, 2 to 3 mg (0.8 to 1.2 ml); and children aged 6 to 14 years, 2.5 to 5 mg (1 to 2 ml) of Verapamil, given intravenously depending on age and response. The injection should be given slowly under electrocardiographic control and only until the effect begins. For intravenous infusion in hypertensive crises, the initial dose is 0.05 to 0.1 mg/kg an hour; if the effect proves insufficient, the dose is increased at 30 to 60 minute intervals until twice the dose or more is reached, up to an average total dose of 1.5 mg/kg a day.