শুধুমাত্র তথ্যমূলক — চিকিৎসা পরামর্শ নয়। সর্বদা লাইসেন্সপ্রাপ্ত স্বাস্থ্যসেবা প্রদানকারীর পরামর্শ নিন।

MedBD
EN
Community data Updated 2 মাস আগে

ইঙ্গিত

Risperdex tablet is indicated for the treatment of acute and chronic psychoses, mania and schizophrenia.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Risperidone is a selective monoaminergic antagonist that binds with high affinity to serotoninergic 5-HT2 and dopaminergic D2 receptors. It also binds to alpha1 adrenergic receptors, and with lower affinity to H1 histamine and alpha2 adrenergic receptors, while showing no affinity for 8 cholinergic receptors. As a potent D2 antagonist, risperidone improves the positive symptoms of schizophrenia while causing less depression of motor activity. Its balanced antagonism of central serotonin and dopamine may lower the risk of extrapyramidal side effects and extend its therapeutic benefit to the negative and affective symptoms of schizophrenia as well.

Pregnancy & Breastfeeding

In experimental animals, Risperidone did not cause direct reproductive toxicity, although some indirect effects mediated through prolactin and the CNS were observed. No study has found any teratogenic effect of Risperidone. The safety of Risperidone during human pregnancy has not been established. Animal studies show that Risperidone and 9-hydroxyrisperidone pass into breast milk, and this has also been demonstrated in human breast milk. For this reason, women taking Risperidone should not breastfeed.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Psychoses: 2 mg in 1 to 2 divided doses on the first day, then 4 mg in 1 to 2 divided doses on the second day (slower titration is appropriate in some patients). The usual dose range is 4 to 6 mg daily. Doses above 10 mg daily should be used only if the benefit is considered to outweigh the risk (maximum 16 mg daily). Elderly patients, or those with hepatic or renal impairment, should start with 1 mg daily in two divided doses, increased in steps of 1 to 2 mg twice daily. Not recommended for children under 15 years. Mania: Initially 2 mg once daily, increased if necessary in steps of 1 mg daily. The usual dose range is 1 to 6 mg daily. Elderly patients, or those with hepatic or renal impairment, should start with 1 mg daily in two divided doses, increased in steps of 1 to 2 mg twice daily. Schizophrenia: Risperidone should generally be started at 1 mg BID (twice daily), with increases in increments of 1 mg BID on the second and third day, as tolerated, to reach a target dose of 3 mg BID by the third day. Further dosage adjustments, if indicated, should generally be made at intervals of not less than 1 week. When dosage adjustments are necessary, small increments or decrements of 1 to 2 mg are recommended.

পার্শ্বপ্রতিক্রিয়া ও পারস্পরিক ক্রিয়া

পার্শ্বপ্রতিক্রিয়া

No side-effect data recorded yet.