শুধুমাত্র তথ্যমূলক — চিকিৎসা পরামর্শ নয়। সর্বদা লাইসেন্সপ্রাপ্ত স্বাস্থ্যসেবা প্রদানকারীর পরামর্শ নিন।

MedBD
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Community data Updated 2 মাস আগে

ইঙ্গিত

Nodia is used in adults to treat active rheumatoid arthritis (RA). It helps reduce the signs and symptoms of the disease and slows the structural joint damage seen on x-ray, such as erosions and narrowing of the joint space.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Leflunomide is an isoxazole immunomodulatory agent which inhibits de novo pyrimidine synthesis and has anti-proliferative activity. Following oral administration, it is rapidly metabolized to A771726, which is active in vitro and is presumed to be the active drug in vivo. Leflunomide has demonstrated prophylactic and therapeutic effects in animal models of autoimmune disease. In addition, leflunomide has exhibited anti-inflammatory and weak analgesic and antipyretic activity. In a model of experimental septicemia, leflunomide did not alter the resistance of mice to bacterial pathogens.

Pregnancy & Breastfeeding

Leflunomide is not recommended for women who are pregnant. Pregnancy must be avoided both during treatment with leflunomide and for some time afterward, until the drug elimination procedure has been completed following treatment. Leflunomide should also not be used by breastfeeding mothers. It is not known whether the drug passes into human breast milk, but since many medicines do, and since leflunomide could potentially cause serious harm to a nursing infant, the decision to continue breastfeeding or to start leflunomide treatment should weigh how important the medicine is to the mother's health.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Leflunomide is taken by mouth once a day for rheumatoid arthritis. Treatment usually starts with a loading dose of 100 mg once daily for the first 3 days, followed by a maintenance dose of 20 mg once daily. Unlike some medicines, leflunomide does not need to be increased gradually in steps. If tolerability problems occur, the dose may be lowered to 10 mg once daily.

পার্শ্বপ্রতিক্রিয়া ও পারস্পরিক ক্রিয়া

পার্শ্বপ্রতিক্রিয়া

No side-effect data recorded yet.

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