ইঙ্গিত
Edema linked to congestive heart failure, liver cirrhosis, premenstrual tension, and swelling caused by various kidney problems (such as nephrotic syndrome, acute glomerulonephritis, and chronic kidney failure). Also used for high blood pressure, whether on its own or alongside other blood pressure medicines.
⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।
ফার্মাকোলজি
Thiazide diuretics such as hydrochlorothiazide help the body shed excess water by blocking the reabsorption of sodium and chloride in the distal convoluted tubules of the kidneys, which increases urine output. This same action also causes the body to lose potassium and raises uric acid levels in the blood.
Hydrochlorothiazide is widely used to treat high blood pressure, though its blood pressure-lowering effect does not appear to come solely from its diuretic action. Long-term use has been shown to reduce the risk of illness and death linked to hypertension, even though the exact mechanism behind this benefit is still not completely understood. Part of the effect seems to come from relaxation of blood vessels, brought about by activating certain large-conductance, calcium-sensitive potassium channels in vascular smooth muscle and by inhibiting carbonic anhydrase enzymes in blood vessel tissue.
Pregnancy & Breastfeeding
Use in pregnancy: Thiazides cross the placenta and can be detected in cord blood. If Hydrochlorothiazide is being considered during pregnancy, or when pregnancy is suspected, the possible benefits to the mother need to be weighed against potential risks to the fetus, including fetal or neonatal jaundice, low platelet counts, and other reactions seen in adults. Diuretics are not recommended for routine use in otherwise healthy pregnant women, whether or not mild swelling is present, since they may lead to reduced blood volume, increased blood thickness, and reduced blood flow to the placenta.
Use in breastfeeding mothers: Thiazides pass into breast milk. If treatment is considered necessary, breastfeeding should be discontinued.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
ডোজ নির্দেশিকা
⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।
পার্শ্বপ্রতিক্রিয়া ও পারস্পরিক ক্রিয়া
পার্শ্বপ্রতিক্রিয়া
No side-effect data recorded yet.