Community data Updated 2 মাস আগে

Dexlansoprazole

Proton Pump Inhibitor Prescription

ইঙ্গিত

Gastroesophageal Reflux Disease

Healing of Erosive Esophagitis: Dexall is used to heal erosive esophagitis (EE) of any grade, with treatment continuing for up to 8 weeks. Maintenance of Healed Erosive Esophagitis: Once healing is achieved, Dexall can be continued for up to 6 months to keep EE healed and to prevent heartburn from returning. Symptomatic Non-Erosive Gastroesophageal Reflux Disease: Dexall is also used to relieve heartburn caused by symptomatic non-erosive GERD, taken for a course of 4 weeks.

⚠️ কোনো ওষুধ গ্রহণের আগে সর্বদা নিবন্ধিত চিকিৎসকের পরামর্শ নিন।

ফার্মাকোলজি

Dexlansoprazole delayed-release capsule belongs to a class of medicines called proton pump inhibitors (PPIs). It reduces the amount of acid made by the stomach by specifically blocking the (H+/K+)-ATPase pump in the acid-producing cells of the stomach lining. Since this pump carries out the last step of acid production, targeting it directly shuts down acid release at its source.

Dexlansoprazole is the R-enantiomer of lansoprazole, which itself is a racemic mixture of R- and S-enantiomers. It is formulated as a Dual Delayed Release (DDR) capsule for oral use, containing two types of enteric-coated granules that dissolve at different pH levels. This design produces two separate absorption peaks in the blood: the first occurs 1 to 2 hours after taking the dose, and the second follows 4 to 5 hours after. After the medicine is taken by mouth, its peak blood concentration (Cmax) and overall exposure (AUC) rise roughly in proportion to the dose given. Dexlansoprazole is broken down mainly by the liver and leaves the body through urine.

Pregnancy & Breastfeeding

Pregnancy Category B. No adequate and well-controlled studies have looked at Dexlansoprazole's use in pregnant women, and the same is true for lactating mothers.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

ডোজ নির্দেশিকা

⚠️ শুধুমাত্র সরকারি উৎস থেকে নির্দেশিকা পরিসীমা। ব্যক্তিগতকৃত ডোজের জন্য আপনার ডাক্তারের পরামর্শ নিন।

Adults: Dexlansoprazole dosing recommendations: for maintenance of healed erosive esophagitis and relief of heartburn, the dose is 30 mg once daily. For symptomatic non-erosive GERD, the dose is 30 mg once daily for 4 weeks. For healing of erosive esophagitis, the dose is 60 mg once daily for up to 8 weeks. Dexlansoprazole MUPS dosing recommendations: for maintenance of healed erosive esophagitis and relief of heartburn, the dose is one 30 mg tablet once daily, taken for 6 months in adults and for 16 weeks in patients 12 to 17 years of age. For symptomatic non-erosive GERD, the dose is one 30 mg tablet once daily for 4 weeks.

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পার্শ্বপ্রতিক্রিয়া

No side-effect data recorded yet.

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