মূল্য
দামগুলো আনুমানিক MRP এবং ফার্মেসিভেদে ভিন্ন হতে পারে। সর্বশেষ নথিভুক্ত দামের সাথে তুলনা করে ট্রেন্ড দেখানো হয়।
সব দামের পরিবর্তন →Isozine
Rx20 mg + 37.5 mg • ট্যাবলেট
ইঙ্গিত ও ব্যবহার
Isozine এর জন্য নির্দেশিত:
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
প্রাপ্তবয়স্ক:
Route of administration: Isozine should be taken in oral route.This tablet should be initiated at a dose of one tablet, three times a day. Dosing should be titrated to a maximum of two tablets three times daily, if tolerated. Although titration of this tablet can be rapid (3-5 days), some patients may experience side effects and may take longer to reach their maximum tolerated dose. The dosage may be decreased to as one-half of this tablet three times a day, if intolerable side effects occur. Efforts should be made to titrate up as soon as side effects subside.Use in children and adolescents: The safety and effectiveness of this combination in children have not been established.
পার্শ্বপ্রতিক্রিয়া
The following adverse reactions have been identified during post-approval use of this tablet- Cardiac Disorders: Palpitations Ear and labyrinth disorders: Tinnitus, vertigo Eye Disorders: Eyelid edema, vision blurred Gastrointestinal Disorders: Abdominal discomfort, constipation General Disorders and Administration Site Conditions: Facial pain, flushing, chest discomfort, chest pain, peripheral edema Musculoskeletal and Connective Tissue Disorders: Pain in extremity, myalgia Nervous Disorders: Dysgeusia, hypoaesthesia, migraine, syncope Renal and Urinary Disorders: Chromaturia, pulmonary renal syndrome Respiratory, Thoracic and Mediastinal Disorders: Dyspnea Reproductive System and Breast Disorders: Erectile dysfunction Skin and Subcutaneous Tissue Disorders: Erythema, hyperhidrosis, pruritus, face swelling
সতর্কতা ও নিষেধাজ্ঞা
সতর্কতা ও সাবধানতা
Symptomatic hypotension, particularly with upright posture, may occur with even small doses of Isozine. Hypotension is most likely to occur in patients who have been volume or salt depleted; it should be corrected prior to initiation of Isozine. Hydralazine hydrochloride has been reported to cause a drug-induced systemic lupus erythematosus (SLE) syndrome. Symptoms and signs usually regress when hydralazine hydrochloride is discontinued. Hydralazine hydrochloride can cause tachycardia and hypotension potentially leading to myocardial ischemia and angina, particularly in patients with hypertrophic cardiomyopathy. Hydralazine hydrochloride has been associated with peripheral neuritis, evidenced by paresthesia, numbness and tingling, which may be related to an antipyridoxine effect. Pyridoxine should be added to Isozine therapy if such symptoms develop.
নিষেধাজ্ঞা
This combination is contraindicated in patients with known hypersensitivity to isosorbide dinitrate or hydralazine hydrochloride or organic nitrates or any other components of this product. It is also contraindicated in patients who are taking PDE-5 inhibitors or soluble guanylate cyclase (sGC) stimulator riociguat.