ইঙ্গিত ও ব্যবহার
Glumol এর জন্য নির্দেশিত:
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
Adults:
The usual starting dose is one drop of 0.25% Timolol in the affected eye twice a day. If the response is not adequate, the dose may be changed to one drop of the 0.50% solution in the affected eye twice a day. In some patients, the pressure-lowering effect of Timolol may take a few weeks to stabilise, so evaluation should include measuring intraocular pressure after approximately 4 weeks of treatment with Timolol. If the intraocular pressure is maintained at a satisfactory level, the dosing schedule may be changed to one drop once a day. Use in children: Clinical studies in children have not been conducted. Timolol Maleate is not recommended in premature babies and newborns.
পার্শ্বপ্রতিক্রিয়া
Timodrop ophthalmic solution is generally well tolerated. In clinical studies of Timodrop, the adverse reactions reported were mainly as follows. Ocular: symptoms of ocular irritation, including conjunctivitis, blepharitis, keratitis, and visual disturbances, including refractive changes (in some cases due to withdrawal of miotic therapy). Cardiovascular: bradycardia, arrhythmia, hypotension, syncope, heart block, cerebrovascular accident, cerebral ischaemia, congestive heart failure, palpitation, and cardiac arrest. Respiratory: bronchospasm, respiratory failure, and dyspnoea. Systemic: headache, nausea, dizziness, depression, and fatigue.
সতর্কতা ও নিষেধাজ্ঞা
Warnings & Precautions
Use with care in patients with inadequate cardiac function, diabetes mellitus (DM), myasthenia gravis, cerebrovascular insufficiency, or a history of atopy. Avoid stopping the medicine abruptly, as this may worsen angina symptoms or precipitate myocardial infarction (MI) in patients with coronary artery disease, or precipitate a thyroid crisis in patients with thyrotoxicosis. Caution is also needed in patients undergoing major surgery. Timolol may mask the signs of hyperthyroidism and hypoglycaemia. The ophthalmic solution should not be used on its own (as monotherapy) for angle-closure glaucoma. Use with care in renal and hepatic impairment, and during pregnancy and lactation.
নিষেধাজ্ঞা
Timolol Maleate must not be used in patients who are known to be hypersensitive to any ingredient of the formulation. It is also strictly contraindicated in bronchial asthma, bronchospasm or severe chronic obstructive pulmonary disease, uncontrolled congestive cardiac insufficiency, cardiogenic shock, high-grade atrioventricular block and marked bradycardia (pulse rate below 45 to 50 beats per minute). Like other eye drops, Timolol Maleate may be absorbed into the bloodstream and produce the systemic effects of beta-blockers. Cardiac insufficiency should therefore be brought under adequate control before treatment with Timolol Maleate is started. In patients with a history of severe heart disease, and in elderly patients, signs of cardiac insufficiency should be watched for and the pulse rate checked. Patients who are already taking an oral beta-blocker and are then given Timolol Maleate should be observed for a possible additive effect, either on intraocular pressure or on the known systemic effects of beta-blockers. Although Timolol Maleate is well tolerated in glaucoma patients who wear contact lenses, and in aphakic patients, contact lens wear should be avoided. This is because beta-blockers reduce tear secretion and some components of the drug may be absorbed onto the lens.