ইঙ্গিত ও ব্যবহার
Cynomin-H এর জন্য নির্দেশিত:
ডোজ নির্দেশিকা
শুধুমাত্র নির্দেশিকা তথ্য
প্রদর্শিত ডোজগুলি সরকারি উৎসের সাধারণ নির্দেশিকা। ব্যক্তিগতকৃত ডোজের জন্য সর্বদা আপনার ডাক্তার বা ফার্মাসিস্টের পরামর্শ নিন।
Adults:
Adults and children may use the following dosage schemes. For Addisonian pernicious anaemia and other macrocytic anaemias without neurological involvement: the initial dose is 250 to 1,000 micrograms by intramuscular injection on alternate days for one to two weeks, then 250 micrograms weekly until the blood count returns to normal. The maintenance dose is 1,000 micrograms monthly. For Addisonian pernicious anaemia and other macrocytic anaemias with neurological complications: the initial dose is 1,000 micrograms by intramuscular injection on alternate days for as long as improvement continues. The maintenance dose is 1,000 micrograms monthly. For prophylaxis of macrocytic anaemia associated with vitamin B12 deficiency arising from gastrectomy, certain malabsorption syndromes, or strict vegetarianism: 250 to 1,000 micrograms monthly. For the Schilling test: an intramuscular injection of 1,000 micrograms of hydroxocobalamin is an essential part of this test.
পার্শ্বপ্রতিক্রিয়া
Sensitisation to Cynomin-H is rare but it may present as an itching rash, chills, fever, hot flushes, nausea, and dizziness, and in exceptional cases as anaphylactic shock. Acneiform and bullous eruptions have also been reported, though rarely.
সতর্কতা ও নিষেধাজ্ঞা
Warnings & Precautions
Cynomin-H should not be given until the diagnosis has been confirmed, if at all possible. The dosage schedules above are usually adequate, but the blood should be checked regularly during treatment. If megaloblastic anaemia does not respond, folate metabolism should be looked into. Doses above 10 micrograms a day can produce a haematological response even in patients who are folate deficient, so giving it indiscriminately may mask the true diagnosis. Cardiac arrhythmias linked to hypokalaemia have been reported during the early stages of therapy, so plasma potassium levels should be monitored over this period.
নিষেধাজ্ঞা
Anaphylaxis; tobacco amblyopia.