Caffeine Riluzole
ModerateCaffeine can slow down the way your body clears riluzole. Caffeine works on an enzyme in the liver called CYP1A2, which helps break riluzole down. When that enzyme is slowed, riluzole may stay in your body longer than usual, so its level could rise. Caffeine is in tea, coffee and some energy drinks and pain relief tablets, so tell your doctor or pharmacist how much you usually have.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.