Ticlopidine Hydrochloride Thiotepa
ModerateTiclopidine can block an enzyme in the liver called CYP2B6. Some other medicines, such as clopidogrel, do the same. Other drugs block a different liver enzyme called CYP3A4. These include azole antifungals, macrolide antibiotics like erythromycin, clarithromycin and telithromycin, and protease inhibitors. Taking any of these with Tepadina (Thiotepa) may raise the level of Thiotepa in your blood. It may also lower the level of TEPA, the active form that Thiotepa breaks down into in the body.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.