Ranolazine Digoxin
ModerateRanolazine (Antogin ER) can slow the clearance of drugs moved by P-gp or broken down by CYP2D6, such as digoxin and TCA. Digoxin may need a lower dose when taken with it.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.