Telithromycin Ceritinib
ModerateTelithromycin is a strong CYP3A inhibitor, so it can raise the level of Ceritinib in your body. If you must take the two together, the Ceritinib dose should be cut by about one third. The new dose is then rounded to the nearest multiple of 150 mg, which is the tablet strength. Other strong CYP3A inhibitors, such as ritonavir, ketoconazole and nefazodone, need the same dose cut. Do not change the dose yourself. Your doctor will work it out.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.