Ethosuximide Fosphenytoin Sodium
ModerateSome medicines can raise the level of phenytoin in the blood. Fosphenytoin turns into phenytoin in the body, so this matters when you take it with ethosuximide. Ethosuximide is on the list of drugs that may increase phenytoin levels. The same list includes acute alcohol intake, amiodarone, chloramphenicol, chlordiazepoxide, cimetidine, diazepam, dicumarol, disulfiram, estrogens, fluoxetine, H2-antagonists, halothane, isoniazid, methylphenidate, phenothiazines, phenylbutazone, salicylates, succinimides, sulfonamides, tolbutamide and trazodone.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.