Oxator Oxaliplatin Sorafenib Tosylate
ModerateJohn’s wort, Phenytoin, Carbamazepine, Phenobarbital, and Dexamethasone) may also increase metabolism of Sofen and thus decrease Sofen concentrations. CYP3A4 Inhibitors and CYP Isoform Substrates: Sofen metabolism is unlikely to be altered by CYP3A4 inhibitors and is unlikely to alter the metabolism of substrates of these enzymes. P-glycoprotein Substrates: Sofen is an inhibitor of P-glycoprotein in vitro, therefore may increase the concentrations of concomitant drugs that are P-glycoprotein subst
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.