Astrogel Estradiol Primidone
ModeratePrimidone is known to make the liver more active at breaking down medicines. Doctors have confirmed this effect, so it is not just a guess. Because Estradiol is one of the medicines the liver processes, taking the two together can change how Estradiol works in your body. If you use both, tell your doctor or pharmacist.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.