Nizoder Ketoconazole Istradefylline
MajorIf you take Istradefylline together with Ketoconazole, a strong CYP 3A4 inhibitor, the dose of Istradefylline should not go above 20 mg once a day. Also, avoid taking it with strong CYP 3A4 inducers such as Rifampicin.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.