Itracap Itraconazole Venetoclax
MajorItraconazole is a strong CYP3A inhibitor. Venetoclax and itraconazole must not be taken together when you start Venetoclax, or while its dose is being slowly stepped up (the titration phase). Using them together at this stage raises the risk of tumour lysis syndrome (TLS), so the combination is contraindicated during this period.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.