Thalidomide and cisplatin can both damage the nerves in your hands and feet (peripheral neuropathy), so taking them together can add up and make the nerve damage worse. This can show up as numbness, tingling, burning or pain, mostly in the fingers and toes. If your doctor prescribes both, use them with caution and tell your doctor early if you notice any of these symptoms.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.